7C1U

Crystal structure of the starter condensation domain of rhizomide synthetase RzmA mutant H140V/R148A in a "product-released" conformation

External Resource: Annotation


Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ACondensation_Ne7c1uA2 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: Condensation_NECOD (1.6)
ACondensation_C_2e7c1uA1 A: a+b complex topologyX: CoA-dependent acyltransferases (From Topology)H: CoA-dependent acyltransferases (From Topology)T: CoA-dependent acyltransferasesF: Condensation_C_2ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00668Condensation domain (Condensation)Condensation domain- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
Non-ribosomal peptide synthetase modules

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
IPR006162Phosphopantetheine attachment sitePTM
IPR009081Phosphopantetheine binding ACP domainDomain
IPR020806Polyketide synthase-like, phosphopantetheine-binding domainDomain
IPR010071Amino acid adenylation domainDomain
IPR029058Alpha/Beta hydrolase foldHomologous Superfamily
IPR020845AMP-binding, conserved siteConserved Site
IPR023213Chloramphenicol acetyltransferase-like domain superfamilyHomologous Superfamily
IPR020802Polyketide synthase, thioesterase domainDomain
IPR045851AMP-binding enzyme, C-terminal domain superfamilyHomologous Superfamily
IPR042099ANL, N-terminal domainHomologous Superfamily
IPR001242Condensation domainDomain
IPR036736ACP-like superfamilyHomologous Superfamily
IPR025110AMP-binding enzyme, C-terminal domainDomain
IPR000873AMP-dependent synthetase/ligase domainDomain
IPR001031ThioesteraseDomain