7KZ5

Crystal structure of KabA from Bacillus cereus UW85 in complex with the plp external aldimine adduct with kanosamine-6-phosphate

External Resource: Annotation

Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	DegT_DnrJ_EryC1	e7kz5A3	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: DegT_DnrJ_EryC1	ECOD (1.6)
A	EUF08651	e7kz5A1	A: a/b three-layered sandwiches	X: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	H: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	T: N-terminal domain in NTD biosynthesis operon protein NtdA	F: EUF08651	ECOD (1.6)
A	Aminotran_5_N	e7kz5A2	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: Aminotran_5_N	ECOD (1.6)
B	DegT_DnrJ_EryC1	e7kz5B3	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: DegT_DnrJ_EryC1	ECOD (1.6)
B	EUF08651	e7kz5B2	A: a/b three-layered sandwiches	X: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	H: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	T: N-terminal domain in NTD biosynthesis operon protein NtdA	F: EUF08651	ECOD (1.6)
B	Aminotran_5_N	e7kz5B1	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: Aminotran_5_N	ECOD (1.6)
C	DegT_DnrJ_EryC1	e7kz5C3	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: DegT_DnrJ_EryC1	ECOD (1.6)
C	EUF08651	e7kz5C1	A: a/b three-layered sandwiches	X: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	H: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	T: N-terminal domain in NTD biosynthesis operon protein NtdA	F: EUF08651	ECOD (1.6)
C	Aminotran_5_N	e7kz5C2	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: Aminotran_5_N	ECOD (1.6)
D	DegT_DnrJ_EryC1	e7kz5D2	A: a+b two layers	X: C-terminal domain in some PLP-dependent transferases (From Topology)	H: C-terminal domain in some PLP-dependent transferases (From Topology)	T: C-terminal domain in some PLP-dependent transferases	F: DegT_DnrJ_EryC1	ECOD (1.6)
D	EUF08651	e7kz5D3	A: a/b three-layered sandwiches	X: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	H: N-terminal domain in NTD biosynthesis operon protein NtdA (From Topology)	T: N-terminal domain in NTD biosynthesis operon protein NtdA	F: EUF08651	ECOD (1.6)
D	Aminotran_5_N	e7kz5D1	A: a/b three-layered sandwiches	X: PLP-dependent transferases (From Topology)	H: PLP-dependent transferases (From Topology)	T: PLP-dependent transferases	F: Aminotran_5_N	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C, D	PF01041	DegT/DnrJ/EryC1/StrS aminotransferase family (DegT_DnrJ_EryC1)	DegT/DnrJ/EryC1/StrS aminotransferase family	The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demons ...	The members of this family are probably all pyridoxal-phosphate-dependent aminotransferase enzymes with a variety of molecular functions. The family includes StsA Swiss:P72454, StsC Swiss:P77952 and StsS [1]. The aminotransferase activity was demonstrated for purified StsC protein as the L-glutamine:scyllo-inosose aminotransferase EC:2.6.1.50, which catalyses the first amino transfer in the biosynthesis of the streptidine subunit of streptomycin [1].	Domain
A, B, C, D	PF22127	NTD biosynthesis operon protein NtdA, N-terminal domain (NtdA_N)	NTD biosynthesis operon protein NtdA, N-terminal domain	This entry represents the N-terminal domain of NtdA, which is not found in other aminotransferases and consists of two-stranded parallel beta-sheet flanked by two alpha-helices [1]. This domain may be involved in protein-protein interactions. NtdA is ...	This entry represents the N-terminal domain of NtdA, which is not found in other aminotransferases and consists of two-stranded parallel beta-sheet flanked by two alpha-helices [1]. This domain may be involved in protein-protein interactions. NtdA is a sugar aminotransferase involved in the biosynthesis of kanosamine.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C, D	Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	transferase activity, transferring nitrogenous groups transaminase activity transferase activity catalytic activity vitamin binding vitamin B6 binding pyridoxal phosphate binding ion binding binding organic cyclic compound binding anion binding heterocyclic compound binding small molecule binding	carbohydrate metabolic process polysaccharide metabolic process biosynthetic process polysaccharide biosynthetic process carbohydrate biosynthetic process metabolic process cellular process primary metabolic process macromolecule metabolic process macromolecule biosynthetic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C, D	IPR015424	Pyridoxal phosphate-dependent transferase	Homologous Superfamily
A, B, C, D	IPR000653	DegT/DnrJ/EryC1/StrS aminotransferase	Family
A, B, C, D	IPR054367	Oxo-glucose-6-phosphate:glutamate aminotransferase, N-terminal domain	Domain
A, B, C, D	IPR015421	Pyridoxal phosphate-dependent transferase, major domain	Homologous Superfamily
A, B, C, D	IPR015422	Pyridoxal phosphate-dependent transferase, small domain	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.