6HJM

Myxococcus xanthus MglB

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d6hjma_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
B	d6hjmb_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
C [auth E]	d6hjme_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
D [auth F]	d6hjmf_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
E [auth C]	d6hjmc_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
F [auth D]	d6hjmd_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
G	d6hjmg_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
H	d6hjmh_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
I	d6hjmi_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
J	d6hjmj_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
K [auth M]	d6hjmm_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
L [auth N]	d6hjmn_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
M [auth Q]	d6hjmq_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
N [auth R]	d6hjmr_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
O [auth K]	d6hjmk_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
P [auth L]	d6hjml_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
Q [auth O]	d6hjmo_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
R [auth P]	d6hjmp_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
T	d6hjmt_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)
S	d6hjms_	Alpha and beta proteins (a+b)	Profilin-like	Roadblock/LC7 domain	automated matches	automated matches	(Myxococcus xanthus ) [TaxId: 34 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
B	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
C [auth E]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
D [auth F]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
E [auth C]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
F [auth D]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
G	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
H	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
I	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
J	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
K [auth M]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
L [auth N]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
M [auth Q]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
N [auth R]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
O [auth K]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
P [auth L]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
Q [auth O]	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
R [auth P]	SCOP2 Family	Roadblock/LC7 domain-like	8099523	4001551	SCOP2 (2022-06-29)
R [auth P]	SCOP2 Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2 (2022-06-29)
T	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)
S	SCOP2B Superfamily	Roadblock/LC7 domain-like	8099524	3001810	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Robl_LC7	e6hjmA1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
B	Robl_LC7	e6hjmB1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
C [auth E]	Robl_LC7	e6hjmE1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
D [auth F]	Robl_LC7	e6hjmF1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
E [auth C]	Robl_LC7	e6hjmC1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
F [auth D]	Robl_LC7	e6hjmD1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
G	Robl_LC7	e6hjmG1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
H	Robl_LC7	e6hjmH1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
I	Robl_LC7	e6hjmI1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
J	Robl_LC7	e6hjmJ1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
K [auth M]	Robl_LC7	e6hjmM1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
L [auth N]	Robl_LC7	e6hjmN1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
M [auth Q]	Robl_LC7	e6hjmQ1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
N [auth R]	Robl_LC7	e6hjmR1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
O [auth K]	Robl_LC7	e6hjmK1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
P [auth L]	Robl_LC7	e6hjmL1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
Q [auth O]	Robl_LC7	e6hjmO1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
R [auth P]	Robl_LC7	e6hjmP1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
T	Robl_LC7	e6hjmT1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)
S	Robl_LC7	e6hjmS1	A: a+b three layers	X: Profilin-like	H: profilin-like (From Topology)	T: profilin-like	F: Robl_LC7	ECOD (1.6)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B, C [auth E], D [auth F], E [auth C], A, B, C [auth E], D [auth F], E [auth C], F [auth D], G, H, I, J, K [auth M], L [auth N], M [auth Q], N [auth R], O [auth K], P [auth L], Q [auth O], R [auth P], S, T	PF03259	Roadblock/LC7 domain (Robl_LC7)	Roadblock/LC7 domain	This family includes proteins that are about 100 amino acids long and have been shown to be related [3]. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is pro ...	This family includes proteins that are about 100 amino acids long and have been shown to be related [3]. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions [2]. This family also includes Swiss:Q9Y2Q5 Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus Swiss:Q50883, a protein involved in gliding motility [4]. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B, C [auth E], D [auth F], E [auth C], A, B, C [auth E], D [auth F], E [auth C], F [auth D], G, H, I, J, K [auth M], L [auth N], M [auth Q], N [auth R], O [auth K], P [auth L], Q [auth O], R [auth P], S, T	MglB	molecular adaptor activity GTPase regulator activity enzyme regulator activity guanyl-nucleotide exchange factor activity nucleoside-triphosphatase regulator activity molecular function regulator activity	cellular response to acid chemical cellular response to stimulus cellular response to amino acid stimulus response to acid chemical cellular response to chemical stimulus response to stimulus response to chemical cellular process response to amino acid positive regulation of cell communication regulation of cellular process positive regulation of signal transduction signaling positive regulation of biological process cellular response to acid chemical cellular response to stimulus cellular response to amino acid stimulus response to acid chemical cellular response to chemical stimulus response to stimulus response to chemical cellular process response to amino acid positive regulation of cell communication regulation of cellular process positive regulation of signal transduction signaling positive regulation of biological process regulation of signal transduction intracellular signal transduction cell communication positive regulation of response to stimulus regulation of intracellular signal transduction positive regulation of TOR signaling signal transduction positive regulation of cellular process TOR signaling regulation of biological process regulation of signaling regulation of TOR signaling biological regulation positive regulation of intracellular signal transduction regulation of response to stimulus regulation of cell communication positive regulation of signaling	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B, C [auth E], D [auth F], E [auth C], A, B, C [auth E], D [auth F], E [auth C], F [auth D], G, H, I, J, K [auth M], L [auth N], M [auth Q], N [auth R], O [auth K], P [auth L], Q [auth O], R [auth P], S, T	IPR037587	Ragulator complex protein LAMTOR2-like	Family
A, B, C [auth E], D [auth F], E [auth C], A, B, C [auth E], D [auth F], E [auth C], F [auth D], G, H, I, J, K [auth M], L [auth N], M [auth Q], N [auth R], O [auth K], P [auth L], Q [auth O], R [auth P], S, T	IPR004942	Roadblock/LAMTOR2 domain	Domain