Annotations: 5J3D

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	C1-set_1	e5j3dA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set_1	ECOD (1.6)
A	V-set_12	e5j3dA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_12	ECOD (1.6)
C	C1-set_1	e5j3dC2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set_1	ECOD (1.6)
C	V-set_12	e5j3dC1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_12	ECOD (1.6)
H	C1-set_1	e5j3dH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set_1	ECOD (1.6)
H	V-set_12	e5j3dH2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_12	ECOD (1.6)
B	C1-set_4	e5j3dB2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set_4	ECOD (1.6)
B	V-set	e5j3dB1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
D	C1-set_4	e5j3dD2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set_4	ECOD (1.6)
D	V-set	e5j3dD1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
L	C1-set_4	e5j3dL1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: C1-set_4	ECOD (1.6)
L	V-set	e5j3dL2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)
G	Fusion_gly_3	e5j3dG1	A: a+b complex topology	X: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)	H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)	T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein	F: Fusion_gly_3	ECOD (1.6)
J	Fusion_gly_3	e5j3dJ1	A: a+b complex topology	X: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)	H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)	T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein	F: Fusion_gly_3	ECOD (1.6)
F	Fusion_gly_4	e5j3dF3	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-like domain in paramyxoviruses fusion protein (From Topology)	T: Immunoglobulin-like domain in paramyxoviruses fusion protein	F: Fusion_gly_4	ECOD (1.6)
I	Fusion_gly_4	e5j3dI1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-like domain in paramyxoviruses fusion protein (From Topology)	T: Immunoglobulin-like domain in paramyxoviruses fusion protein	F: Fusion_gly_4	ECOD (1.6)
I	Fusion_gly	e5j3dI2	A: a+b complex topology	X: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)	H: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein (From Topology)	T: Head and neck region of the ectodomain of paramyxoviruses fusion glycoprotein	F: Fusion_gly	ECOD (1.6)

IMGT Antibody Annotation IMGT Database Homepage

Chain	Protein Name	Description	Organism Name	Gene Allele Name(s)	Domain Name(s)	Receptor Type	Receptor Description	Provenance Source
A, C, H	Fab 14N4	VH-CH1	Homo sapiens (human)	IGHV3-5301, IGHJ301, IGHG1*03	V-DOMAIN VH, C-DOMAIN CH1	IG	FAB-GAMMA-1_KAPPA	IMGT (202448-0)
B, D, L	Fab 14N4	L-KAPPA	Homo sapiens (human)	IGKV1-501, IGKJ101, IGKC*01	V-DOMAIN V-KAPPA, C-DOMAIN C-KAPPA	IG	FAB-GAMMA-1_KAPPA	IMGT (202448-0)

SAbDab Antibody Annotation SAbDab Database Homepage

Chain	Chain Class	Chain Subclass	Chain Type	Antigen Name(s)	Provenance Source
A, C, H	Heavy Chain	IGHV3	-	fusion glycoprotein f0 \| fusion glycoprotein f0	SAbDab (2024-12-06)
B, D, L	Light Chain	IGKV1	Kappa	fusion glycoprotein f0 \| fusion glycoprotein f0	SAbDab (2024-12-06)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
F, I, K	PF00523	Fusion glycoprotein F0 (Fusion_gly)	Fusion glycoprotein F0	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, C, H	14N4 heavy chain	-	-	-
B, D, L	14N4 light chain	-	-	-
E, G, J	Fusion glycoprotein F0	identical protein binding protein binding binding	membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host symbiont-mediated induction of syncytium formation symbiont-mediated perturbation of host process modulation of process of another organism	cell periphery cellular anatomical structure plasma membrane membrane virion component viral membrane viral envelope host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane cell periphery cellular anatomical structure plasma membrane membrane virion component viral membrane viral envelope host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane host cell Golgi apparatus host cell cytoplasm part host cell cytoplasm host cell endomembrane system host intracellular region
F, I, K	Fusion glycoprotein F0	identical protein binding protein binding binding	membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle membrane organization cellular component organization membrane fusion fusion of virus membrane with host plasma membrane viral process cellular process cellular component organization or biogenesis membrane fusion involved in viral entry into host cell virion attachment to host cell biological process involved in interspecies interaction between organisms receptor-mediated virion attachment to host cell adhesion of symbiont to host cell entry receptor-mediated virion attachment to host cell viral life cycle adhesion of symbiont to host biological process involved in interaction with host biological process involved in symbiotic interaction symbiont entry into host cell symbiont entry into host symbiont-mediated induction of syncytium formation symbiont-mediated perturbation of host process modulation of process of another organism	cell periphery cellular anatomical structure plasma membrane membrane virion component viral membrane viral envelope host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane cell periphery cellular anatomical structure plasma membrane membrane virion component viral membrane viral envelope host cell plasma membrane host cellular component host cell part host cell membrane virion membrane host intracellular part host cell Golgi membrane host cell Golgi apparatus host cell cytoplasm part host cell cytoplasm host cell endomembrane system host intracellular region

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
E, G, J	IPR000776	Precursor fusion glycoprotein F0, Paramyxoviridae	Family
F, I, K	IPR000776	Precursor fusion glycoprotein F0, Paramyxoviridae	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.