4OR0

Crystal Structure of Bovine Serum Albumin in complex with naproxen

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
B	d4or0b1	All alpha proteins	Serum albumin-like	Serum albumin-like	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)
A	d4or0a1	All alpha proteins	Serum albumin-like	Serum albumin-like	automated matches	automated matches	(Bos taurus ) [TaxId: 9913 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
B	Serum_albumin	e4or0B2	A: alpha complex topology	X: Serum albumin-like (From Topology)	H: Serum albumin-like (From Topology)	T: Serum albumin-like	F: Serum_albumin	ECOD (1.6)
A	Serum_albumin	e4or0A2	A: alpha complex topology	X: Serum albumin-like (From Topology)	H: Serum albumin-like (From Topology)	T: Serum albumin-like	F: Serum_albumin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
B	1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin	Chain A, Domain 1	CATH (4.3.0)
A	1.10.246.10	Mainly Alpha	Orthogonal Bundle	Serum Albumin	Chain A, Domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF00273	Serum albumin family (Serum_albumin)	Serum albumin family	-	Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Serum albumin	DNA binding binding organic cyclic compound binding nucleic acid binding vitamin binding vitamin B6 binding pyridoxal phosphate binding ion binding anion binding heterocyclic compound binding small molecule binding fatty acid binding organic acid binding lipid binding DNA binding binding organic cyclic compound binding nucleic acid binding vitamin binding vitamin B6 binding pyridoxal phosphate binding ion binding anion binding heterocyclic compound binding small molecule binding fatty acid binding organic acid binding lipid binding carboxylic acid binding monocarboxylic acid binding toxic substance binding macrolide binding enterobactin binding cation binding metal ion binding	cellular response to stimulus cellular response to nutrient levels response to nutrient levels response to stimulus cellular response to stress response to stress cellular process response to starvation cellular response to starvation regulation of biological process regulation of cellular process regulation of mitochondrial depolarization negative regulation of membrane depolarization biological regulation cellular response to stimulus cellular response to nutrient levels response to nutrient levels response to stimulus cellular response to stress response to stress cellular process response to starvation cellular response to starvation regulation of biological process regulation of cellular process regulation of mitochondrial depolarization negative regulation of membrane depolarization biological regulation negative regulation of biological process mitochondrial depolarization regulation of membrane depolarization regulation of mitochondrial membrane potential membrane depolarization regulation of biological quality negative regulation of mitochondrial depolarization regulation of membrane potential cellular response to calcium ion starvation	cellular anatomical structure extracellular region intracellular anatomical structure cytoplasm extracellular space protein-containing complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR020857	Serum albumin, conserved site	Conserved Site
A, B	IPR000264	ALB/AFP/VDB	Family
A, B	IPR014760	Serum albumin, N-terminal	Domain
A, B	IPR020858	Serum albumin-like	Homologous Superfamily
A, B	IPR021177	Serum albumin/Alpha-fetoprotein/Afamin	Family

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.