Annotations: 4JZP

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Bap31/Bap29 transmembrane region-like	8106672	3002862	SCOP2B (2022-06-29)
B	SCOP2 Family	Bap31/Bap29 transmembrane region-like	8047314	4005569	SCOP2 (2022-06-29)
B	SCOP2 Superfamily	Bap31/Bap29 transmembrane region-like	8106672	3002862	SCOP2 (2022-06-29)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF18035	Bap31/Bap29 cytoplasmic coiled-coil domain (Bap31_Bap29_C)	Bap31/Bap29 cytoplasmic coiled-coil domain	-	Coiled-coil

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	B-cell receptor-associated protein 31	protein-containing complex binding binding protein binding MHC class I protein binding signaling receptor binding MHC protein binding	protein localization establishment of protein localization cellular localization protein targeting establishment of localization localization establishment of protein localization to organelle cellular macromolecule localization macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion protein localization establishment of protein localization cellular localization protein targeting establishment of localization localization establishment of protein localization to organelle cellular macromolecule localization macromolecule localization protein localization to organelle protein localization to mitochondrion protein targeting to mitochondrion cellular process establishment of protein localization to mitochondrion developmental process spermatogenesis sexual reproduction reproductive process multicellular organismal reproductive process developmental process involved in reproduction male gamete generation gamete generation regulation of cellular process catabolic process positive regulation of protein metabolic process proteolysis involved in protein catabolic process positive regulation of biological process macromolecule catabolic process regulation of ubiquitin-dependent protein catabolic process regulation of primary metabolic process positive regulation of metabolic process positive regulation of ubiquitin-dependent protein catabolic process regulation of proteolysis regulation of proteolysis involved in protein catabolic process modification-dependent macromolecule catabolic process proteolysis positive regulation of macromolecule metabolic process protein metabolic process positive regulation of cellular process regulation of biological process regulation of protein metabolic process biological regulation primary metabolic process regulation of macromolecule metabolic process protein catabolic process regulation of catabolic process positive regulation of proteolysis involved in protein catabolic process positive regulation of catabolic process modification-dependent protein catabolic process positive regulation of proteolysis metabolic process ubiquitin-dependent protein catabolic process macromolecule metabolic process regulation of metabolic process apoptotic process cell death programmed cell death cellular response to stimulus regulation of localization nitrogen compound transport response to stimulus positive regulation of establishment of protein localization ERAD pathway establishment of localization in cell positive regulation of retrograde protein transport, ER to cytosol regulation of intracellular transport response to endoplasmic reticulum stress intracellular transport response to nitrogen compound response to chemical positive regulation of protein localization regulation of intracellular protein transport positive regulation of intracellular protein transport intracellular protein transport regulation of protein exit from endoplasmic reticulum protein exit from endoplasmic reticulum regulation of protein localization transport regulation of retrograde protein transport, ER to cytosol positive regulation of protein transport cellular response to stress response to stress positive regulation of intracellular transport endoplasmic reticulum to cytosol transport regulation of transport regulation of establishment of protein localization proteasomal protein catabolic process regulation of protein transport positive regulation of protein exit from endoplasmic reticulum positive regulation of transport protein transport regulation of cellular localization retrograde protein transport, ER to cytosol endoplasmic reticulum to Golgi vesicle-mediated transport Golgi vesicle transport vesicle-mediated transport protein localization to endoplasmic reticulum exit site protein localization to endoplasmic reticulum positive regulation of cell communication positive regulation of signal transduction signaling regulation of signal transduction regulation of programmed cell death regulation of intrinsic apoptotic signaling pathway intracellular signal transduction cell communication positive regulation of apoptotic signaling pathway positive regulation of response to stimulus regulation of intracellular signal transduction signal transduction intrinsic apoptotic signaling pathway regulation of signaling positive regulation of programmed cell death regulation of apoptotic process positive regulation of intracellular signal transduction positive regulation of apoptotic process apoptotic signaling pathway regulation of response to stimulus regulation of cell communication positive regulation of intrinsic apoptotic signaling pathway regulation of apoptotic signaling pathway positive regulation of signaling positive regulation of proteasomal protein catabolic process regulation of cellular response to stress regulation of ERAD pathway positive regulation of protein catabolic process regulation of proteasomal protein catabolic process positive regulation of ERAD pathway regulation of response to endoplasmic reticulum stress positive regulation of response to endoplasmic reticulum stress regulation of response to stress regulation of protein catabolic process	organelle membrane contact site cellular anatomical structure organelle mitochondria-associated endoplasmic reticulum membrane contact site membrane membrane-bounded organelle intracellular anatomical structure intracellular vesicle intracellular membrane-bounded organelle intracellular organelle cytoplasmic vesicle clathrin-coated vesicle coated vesicle cytoplasm organelle membrane contact site cellular anatomical structure organelle mitochondria-associated endoplasmic reticulum membrane contact site membrane membrane-bounded organelle intracellular anatomical structure intracellular vesicle intracellular membrane-bounded organelle intracellular organelle cytoplasmic vesicle clathrin-coated vesicle coated vesicle cytoplasm vesicle cytosol Golgi cisterna membrane Golgi apparatus subcompartment Golgi apparatus organelle subcompartment Golgi cisterna endomembrane system Golgi stack organelle membrane cell periphery plasma membrane perinuclear endoplasmic reticulum perinuclear region of cytoplasm endoplasmic reticulum endoplasmic reticulum subcompartment nuclear outer membrane-endoplasmic reticulum membrane network endoplasmic reticulum membrane lumenal side of endoplasmic reticulum membrane side of membrane lumenal side of membrane Golgi membrane bounding membrane of organelle endoplasmic reticulum-Golgi intermediate compartment membrane endoplasmic reticulum-Golgi intermediate compartment lipid droplet membraneless organelle intracellular membraneless organelle

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR040463	BAP29/BAP31, transmembrane domain	Domain
A, B	IPR008417	B-cell receptor-associated protein 29/31	Family
A, B	IPR041672	Bap31/Bap29 cytoplasmic coiled-coil domain	Domain

Pharos: Disease Associations Pharos Homepage Annotation

Chains	Drug Target	Associated Disease
A, B	Pharos: P51572	severe motor and intellectual disabilities-sensorineural deafness-dystonia syndrome dystonic disorder intellectual disability Contiguous Abcd1-Dxs1375e Deletion Syndrome ovarian cancer plasma cell myeloma diabetes mellitus leukodystrophy

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.