4ADL
Crystal structures of Rv1098c in complex with malate
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | d4adla_ | All alpha proteins | L-aspartase-like | L-aspartase-like | automated matches | automated matches | (Mycobacterium tuberculosis H37Rv ) [TaxId: 83332 ], | SCOPe (2.08) |
C | d4adlc_ | All alpha proteins | L-aspartase-like | L-aspartase-like | automated matches | automated matches | (Mycobacterium tuberculosis H37Rv ) [TaxId: 83332 ], | SCOPe (2.08) |
D | d4adld_ | All alpha proteins | L-aspartase-like | L-aspartase-like | automated matches | automated matches | (Mycobacterium tuberculosis H37Rv ) [TaxId: 83332 ], | SCOPe (2.08) |
B | d4adlb_ | All alpha proteins | L-aspartase-like | L-aspartase-like | automated matches | automated matches | (Mycobacterium tuberculosis H37Rv ) [TaxId: 83332 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | L-aspartase-like | 8072365 | 3001572 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | L-aspartase-like | 8072365 | 3001572 | SCOP2B (2022-06-29) |
D | SCOP2B Superfamily | L-aspartase-like | 8072365 | 3001572 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | L-aspartase-like | 8072365 | 3001572 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | Lyase_1_N | e4adlA2 | A: alpha arrays | X: L-aspartase N-terminal domain-like (From Topology) | H: L-aspartase N-terminal domain-like (From Topology) | T: L-aspartase N-terminal domain-like | F: Lyase_1_N | ECOD (1.6) |
A | FumaraseC_C | e4adlA3 | A: alpha arrays | X: L-aspartase C-terminal domain-like (From Homology) | H: L-aspartase C-terminal domain-like | T: L-aspartase C-terminal domain-like | F: FumaraseC_C | ECOD (1.6) |
A | Lyase_1_C | e4adlA1 | A: alpha arrays | X: L-aspartase middle domain-like | H: L-aspartase middle domain-like (From Topology) | T: L-aspartase middle domain-like | F: Lyase_1_C | ECOD (1.6) |
C | Lyase_1_N | e4adlC9 | A: alpha arrays | X: L-aspartase N-terminal domain-like (From Topology) | H: L-aspartase N-terminal domain-like (From Topology) | T: L-aspartase N-terminal domain-like | F: Lyase_1_N | ECOD (1.6) |
C | FumaraseC_C | e4adlC7 | A: alpha arrays | X: L-aspartase C-terminal domain-like (From Homology) | H: L-aspartase C-terminal domain-like | T: L-aspartase C-terminal domain-like | F: FumaraseC_C | ECOD (1.6) |
C | Lyase_1_C | e4adlC8 | A: alpha arrays | X: L-aspartase middle domain-like | H: L-aspartase middle domain-like (From Topology) | T: L-aspartase middle domain-like | F: Lyase_1_C | ECOD (1.6) |
D | Lyase_1_N | e4adlD9 | A: alpha arrays | X: L-aspartase N-terminal domain-like (From Topology) | H: L-aspartase N-terminal domain-like (From Topology) | T: L-aspartase N-terminal domain-like | F: Lyase_1_N | ECOD (1.6) |
D | FumaraseC_C | e4adlD7 | A: alpha arrays | X: L-aspartase C-terminal domain-like (From Homology) | H: L-aspartase C-terminal domain-like | T: L-aspartase C-terminal domain-like | F: FumaraseC_C | ECOD (1.6) |
D | Lyase_1_C | e4adlD8 | A: alpha arrays | X: L-aspartase middle domain-like | H: L-aspartase middle domain-like (From Topology) | T: L-aspartase middle domain-like | F: Lyase_1_C | ECOD (1.6) |
B | Lyase_1_N | e4adlB9 | A: alpha arrays | X: L-aspartase N-terminal domain-like (From Topology) | H: L-aspartase N-terminal domain-like (From Topology) | T: L-aspartase N-terminal domain-like | F: Lyase_1_N | ECOD (1.6) |
B | FumaraseC_C | e4adlB7 | A: alpha arrays | X: L-aspartase C-terminal domain-like (From Homology) | H: L-aspartase C-terminal domain-like | T: L-aspartase C-terminal domain-like | F: FumaraseC_C | ECOD (1.6) |
B | Lyase_1_C | e4adlB8 | A: alpha arrays | X: L-aspartase middle domain-like | H: L-aspartase middle domain-like (From Topology) | T: L-aspartase middle domain-like | F: Lyase_1_C | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00206 | Lyase (Lyase_1) | Lyase | - | Domain | |
PF10415 | Fumarase C C-terminus (FumaraseC_C) | Fumarase C C-terminus | Fumarase C catalyses the stereo-specific interconversion of fumarate to L-malate as part of the Kreb's cycle. The full-length protein forms a tetramer with visible globular shape. FumaraseC_C is the C-terminal 65 residues referred to as domain 3. The ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR000362 | Fumarate lyase family | Family | |
IPR022761 | Fumarate lyase, N-terminal | Domain | |
IPR024083 | Fumarase/histidase, N-terminal | Homologous Superfamily | |
IPR005677 | Fumarate hydratase, class II | Family | |
IPR008948 | L-Aspartase-like | Homologous Superfamily | |
IPR018951 | Fumarase C, C-terminal | Domain | |
IPR020557 | Fumarate lyase, conserved site | Conserved Site |