3SWS

Crystal Structure of the Quinone Form of Methylamine Dehydrogenase in Complex with the Diferric Form of MauG

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Protein Modification Annotation

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C	d3swsc1	Small proteins	Methylamine dehydrogenase, L chain	Methylamine dehydrogenase, L chain	Methylamine dehydrogenase, L chain	Methylamine dehydrogenase	(Paracoccus denitrificans PD1222 ) [TaxId: 318586 ],	SCOPe (2.08)
C	d3swsc2	Artifacts	Tags	Tags	Tags	C-terminal Tags	(Paracoccus denitrificans PD1222 ) [TaxId: 318586 ],	SCOPe (2.08)
E	d3swse_	Small proteins	Methylamine dehydrogenase, L chain	Methylamine dehydrogenase, L chain	Methylamine dehydrogenase, L chain	Methylamine dehydrogenase	(Paracoccus denitrificans PD1222 ) [TaxId: 318586 ],	SCOPe (2.08)
D	d3swsd_	All beta proteins	7-bladed beta-propeller	YVTN repeat-like/Quinoprotein amine dehydrogenase	automated matches	automated matches	(Paracoccus denitrificans PD1222 ) [TaxId: 318586 ],	SCOPe (2.08)
F	d3swsf_	All beta proteins	7-bladed beta-propeller	YVTN repeat-like/Quinoprotein amine dehydrogenase	automated matches	automated matches	(Paracoccus denitrificans PD1222 ) [TaxId: 318586 ],	SCOPe (2.08)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	CCP_MauG	e3swsA3	A: alpha arrays	X: Cytochrome c-like	H: Cytochrome c (From Topology)	T: Cytochrome c	F: CCP_MauG	ECOD (1.6)
A	DHOR	e3swsA2	A: alpha arrays	X: Cytochrome c-like	H: Cytochrome c (From Topology)	T: Cytochrome c	F: DHOR	ECOD (1.6)
B	CCP_MauG	e3swsB3	A: alpha arrays	X: Cytochrome c-like	H: Cytochrome c (From Topology)	T: Cytochrome c	F: CCP_MauG	ECOD (1.6)
B	DHOR	e3swsB2	A: alpha arrays	X: Cytochrome c-like	H: Cytochrome c (From Topology)	T: Cytochrome c	F: DHOR	ECOD (1.6)
C	Me-amine-dh_L	e3swsC1	A: few secondary structure elements	X: Methylamine dehydrogenase, L chain (From Topology)	H: Methylamine dehydrogenase, L chain (From Topology)	T: Methylamine dehydrogenase, L chain	F: Me-amine-dh_L	ECOD (1.6)
E	Me-amine-dh_L	e3swsE1	A: few secondary structure elements	X: Methylamine dehydrogenase, L chain (From Topology)	H: Methylamine dehydrogenase, L chain (From Topology)	T: Methylamine dehydrogenase, L chain	F: Me-amine-dh_L	ECOD (1.6)
D	Me-amine-dh_H	e3swsD1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: Me-amine-dh_H	ECOD (1.6)
F	Me-amine-dh_H	e3swsF1	A: beta duplicates or obligate multimers	X: beta-propeller-like	H: beta-propeller	T: 7-bladed	F: Me-amine-dh_H	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	1.10.760.10	Mainly Alpha	Orthogonal Bundle	Cytochrome Bc1 Complex	Chain D, domain 2	CATH (4.3.0)
B	1.10.760.10	Mainly Alpha	Orthogonal Bundle	Cytochrome Bc1 Complex	Chain D, domain 2	CATH (4.3.0)
C	2.60.30.10	Mainly Beta	Sandwich	Electron Transport Ethylamine Dehydrogenase	Methylamine/Aralkylamine dehydrogenase light chain	CATH (4.3.0)
E	2.60.30.10	Mainly Beta	Sandwich	Electron Transport Ethylamine Dehydrogenase	Methylamine/Aralkylamine dehydrogenase light chain	CATH (4.3.0)
D	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)
F	2.130.10.10	Mainly Beta	7 Propeller	Methylamine Dehydrogenase	Chain H	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF03150	Di-haem cytochrome c peroxidase (CCP_MauG)	Di-haem cytochrome c peroxidase	-	Family
C, E	PF02975	Methylamine dehydrogenase, L chain (Me-amine-dh_L)	Methylamine dehydrogenase, L chain		Domain
D, F	PF06433	Methylamine dehydrogenase heavy chain (MADH) (Me-amine-dh_H)	Methylamine dehydrogenase heavy chain (MADH)	-	Repeat

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	Methylamine utilization protein MauG	peroxidase activity oxidoreductase activity cytochrome-c peroxidase activity antioxidant activity oxidoreductase activity, acting on peroxide as acceptor catalytic activity binding tetrapyrrole binding heme binding electron transfer activity cation binding ion binding metal ion binding small molecule binding	-	cellular anatomical structure periplasmic space
C, E	Methylamine dehydrogenase light chain	oxidoreductase activity, acting on the CH-NH2 group of donors oxidoreductase activity methylamine dehydrogenase (amicyanin) activity oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor catalytic activity aliphatic amine dehydrogenase activity	amine metabolic process metabolic process cellular process	cellular anatomical structure outer membrane-bounded periplasmic space cell envelope periplasmic space
D, F	Methylamine dehydrogenase heavy chain	oxidoreductase activity, acting on the CH-NH2 group of donors oxidoreductase activity methylamine dehydrogenase (amicyanin) activity oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor catalytic activity aliphatic amine dehydrogenase activity	amine metabolic process methylamine metabolic process metabolic process cellular process primary amino compound metabolic process	cellular anatomical structure periplasmic space

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR004852	Di-haem cytochrome c peroxidase	Domain
A, B	IPR036909	Cytochrome c-like domain superfamily	Homologous Superfamily
A, B	IPR026259	Di-c-type haem protein, MauG/cytochrome c peroxidase	Family
A, B	IPR009056	Cytochrome c-like domain	Domain
A, B	IPR051395	Cytochrome c-dependent Peroxidase and MauG	Family
C, E	IPR004229	Methylamine dehydrogenase light chain	Family
C, E	IPR016008	Amine dehydrogenase light chain	Family
C, E	IPR036560	Methylamine/Aralkylamine dehydrogenase light chain superfamily	Homologous Superfamily
C, E	IPR013504	Methylamine/Aralkylamine dehydrogenase light chain, C-terminal domain	Domain
D, F	IPR009451	Amine dehydrogenase heavy chain	Family
D, F	IPR011044	Quinoprotein amine dehydrogenase, beta chain-like	Homologous Superfamily
D, F	IPR015943	WD40/YVTN repeat-like-containing domain superfamily	Homologous Superfamily
D, F	IPR013476	Methylamine dehydrogenase heavy chain	Family

Protein Modification Annotation

Modified Residue(s)
Chain	Residue(s)	Description
C, E	TRQ	Parent Component: TRP RESID: AA0148 PSI-MOD : oxidation of tryptophan to L-tryptophyl quinone MOD:00157

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.