Annotations: 3JCX

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	Parvo_coat	e3jcxA1	A: beta sandwiches	X: jelly-roll	H: Nucleoplasmin-like/VP (viral coat and capsid proteins) (From Topology)	T: Nucleoplasmin-like/VP (viral coat and capsid proteins)	F: Parvo_coat	ECOD (1.6)
B [auth H]	V-set_8	e3jcxH1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set_8	ECOD (1.6)
C [auth L]	V-set	e3jcxL1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: V-set	ECOD (1.6)

IMGT Antibody Annotation IMGT Database Homepage

Chain	Protein Name	Description	Organism Name	Gene Allele Name(s)	Domain Name(s)	Receptor Type	Receptor Description	Provenance Source
B [auth H]	Fab E	VH	Rattus norvegicus (Norway rat)	IGHV2-3201, IGHJ301	V-DOMAIN VH	IG	FV-HEAVY_KAPPA	IMGT (202510-0)
C [auth L]	Fab E	V-KAPPA	Rattus norvegicus (Norway rat)	IGKV6S1001, IGKJ501	V-DOMAIN V-KAPPA	IG	FV-HEAVY_KAPPA	IMGT (202510-0)

SAbDab Antibody Annotation SAbDab Database Homepage

Chain	Chain Class	Chain Subclass	Chain Type	Antigen Name(s)	Provenance Source
B [auth H]	Heavy Chain	IGHV2	-	capsid protein 2	SAbDab (2025-03-21)
C [auth L]	Light Chain	IGKV6	Kappa	capsid protein 2	SAbDab (2025-03-21)

Thera-SAbDab Antibody Annotation Thera-SAbDab Database Homepage

Chain	Name	Target	Provenance Source
B [auth H]	Anivovetmab	Minor Capsid VP2 (Canine)	Therapeutic SAbDab (2025-03-21)
C [auth L]	Anivovetmab	Minor Capsid VP2 (Canine)	Therapeutic SAbDab (2025-03-21)

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	Capsid protein 2	structural molecule activity	import into cell receptor-mediated endocytosis of virus by host cell biological process involved in interspecies interaction between organisms transport viral life cycle establishment of localization vesicle-mediated transport biological process involved in interaction with host biological process involved in symbiotic interaction localization symbiont entry into host cell clathrin-dependent endocytosis viral process symbiont entry into host import into cell receptor-mediated endocytosis of virus by host cell biological process involved in interspecies interaction between organisms transport viral life cycle establishment of localization vesicle-mediated transport biological process involved in interaction with host biological process involved in symbiotic interaction localization symbiont entry into host cell clathrin-dependent endocytosis viral process symbiont entry into host cellular process clathrin-dependent endocytosis of virus by host cell receptor-mediated endocytosis endocytosis endocytosis involved in viral entry into host cell virion attachment to host cell adhesion of symbiont to host cell adhesion of symbiont to host symbiont-mediated disruption of host anatomical structure symbiont entry into host cell via permeabilization of host membrane symbiont-mediated disruption of host cellular anatomical structure symbiont-mediated perturbation of host membrane disruption of anatomical structure in another organism	viral capsid icosahedral viral capsid virion component T=1 icosahedral viral capsid
B [auth H]	Fab E heavy chain	-	-	-
C [auth L]	Fab E light chain	-	-	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR016184	Capsid/spike protein, ssDNA virus	Homologous Superfamily
A	IPR036952	Parvovirus coat protein VP1/VP2	Homologous Superfamily
A	IPR001403	Parvovirus coat protein VP2	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.