Structure of human anti-nicotine Fab fragment in complex with nicotine
External Resource: Annotation
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
A [auth H] | V-set_8 | e2yk1H2 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: V-set_8 | ECOD (1.6) |
A [auth H] | C1-set_1 | e2yk1H1 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set_1 | ECOD (1.6) |
B [auth L] | C1-set | e2yk1L3 | A: beta sandwiches | X: Immunoglobulin-like beta-sandwich | H: Immunoglobulin-related | T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like | F: C1-set | ECOD (1.6) |
Chain | Protein Name | Description | Organism Name | Gene Allele Name(s) | Domain Name(s) | Receptor Type | Receptor Description | Provenance Source |
---|
A [auth H] | FAB FRAGMENT | VH-CH1 | Homo sapiens (human) | IGHV4-39*01, IGHV4-39*07, IGHJ1*01, IGHJ5*01, IGHJ5*02, IGHG2*01, IGHG2*06, IGHG2*05, IGHG2*03 | V-DOMAIN VH, C-DOMAIN CH1 | IG | FAB-GAMMA-2_LAMBDA | IMGT (202448-0) |
B [auth L] | FAB FRAGMENT | L-LAMBDA | Homo sapiens (human) | IGLV1-47*01, IGLJ7*01, IGLJ7*02, IGLC2*01, IGLC2*02, IGLC3*04 | V-DOMAIN V-LAMBDA, C-DOMAIN C-LAMBDA | IG | FAB-GAMMA-2_LAMBDA | IMGT (202448-0) |
Chain | Chain Class | Chain Subclass | Chain Type | Antigen Name(s) | Provenance Source |
---|
A [auth H] | Heavy Chain | IGHV4 | - | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE | SAbDab (2024-12-06) |
B [auth L] | Light Chain | IGLV1 | Lambda | (S)-3-(1-METHYLPYRROLIDIN-2-YL)PYRIDINE | SAbDab (2024-12-06) |