2W1N | pdb_00002w1n

cohesin and fibronectin type-III double module construct from the Clostridium perfringens glycoside hydrolase GH84C

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2B Superfamily	Carbohydrate-binding domain	8035281	3000706	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	fn3_8	e2w1nA2	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Immunoglobulin/Fibronectin type III/E set domains/PapD-like	F: fn3_8	ECOD (1.6)
A	Cohesin	e2w1nA1	A: beta sandwiches	X: Immunoglobulin-like beta-sandwich	H: Immunoglobulin-related	T: Common fold of diphtheria toxin/transcription factors/cytochrome f	F: Cohesin	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.60.40.680	Mainly Beta	Sandwich	Immunoglobulin-like		CATH (4.3.0)
A	2.60.40.10	Mainly Beta	Sandwich	Immunoglobulin-like	Immunoglobulins	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF00963	Cohesin domain (Cohesin)	Cohesin domain	Cohesin domains interact with a complementary domain, termed the dockerin domain. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome [1].	Domain
A	PF00041	Fibronectin type III domain (fn3)	Fibronectin type III domain		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	O-GLCNACASE NAGJ	binding carbohydrate binding hydrolase activity, acting on glycosyl bonds hexosaminidase activity beta-N-acetylhexosaminidase activity beta-N-acetylglucosaminidase activity hydrolase activity, hydrolyzing O-glycosyl compounds hydrolase activity catalytic activity [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity catalytic activity, acting on a protein	carbohydrate metabolic process primary metabolic process metabolic process cellular process macromolecule modification protein deglycosylation carbohydrate derivative metabolic process protein metabolic process macromolecule metabolic process protein modification process glycoprotein metabolic process polysaccharide metabolic process catabolic process polysaccharide catabolic process carbohydrate metabolic process primary metabolic process metabolic process cellular process macromolecule modification protein deglycosylation carbohydrate derivative metabolic process protein metabolic process macromolecule metabolic process protein modification process glycoprotein metabolic process polysaccharide metabolic process catabolic process polysaccharide catabolic process carbohydrate catabolic process macromolecule catabolic process	-

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR051822	Glycosyl Hydrolase Family 84	Family
A	IPR017853	Glycoside hydrolase superfamily	Homologous Superfamily
A	IPR003961	Fibronectin type III	Domain
A	IPR029018	Beta-hexosaminidase-like, domain 2	Homologous Superfamily
A	IPR011496	Beta-N-acetylglucosaminidase, catalytic domain	Domain
A	IPR008965	CBM2/CBM3, carbohydrate-binding domain superfamily	Homologous Superfamily
A	IPR008979	Galactose-binding-like domain superfamily	Homologous Superfamily
A	IPR002102	Cellulosome anchoring protein, cohesin domain	Domain
A	IPR000421	Coagulation factor 5/8, C-terminal domain	Domain
A	IPR013783	Immunoglobulin-like fold	Homologous Superfamily
A	IPR015882	Beta-hexosaminidase, bacterial type, N-terminal	Domain
A	IPR049019	NagJ-like, helical domain	Domain
A	IPR036116	Fibronectin type III superfamily	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.