Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
BSCOP2B SuperfamilyCytochrome c 8099084 3000815 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyCytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 8101132 3000762 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyCytochrome c 8099084 3000815 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyCytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 8101132 3000762 SCOP2B (2022-06-29)
NSCOP2B SuperfamilyCytochrome c 8099084 3000815 SCOP2B (2022-06-29)
NSCOP2B SuperfamilyCytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 8101132 3000762 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyCytochrome c 8099084 3000815 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyCytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 8101132 3000762 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyCytochrome c 8099084 3000815 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyCytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 8101132 3000762 SCOP2B (2022-06-29)
QSCOP2B SuperfamilyCytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor 8101132 3000762 SCOP2B (2022-06-29)
QSCOP2B SuperfamilyCytochrome c 8099084 3000815 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyISP transmembrane anchor 8052868 3000753 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyISP domain 8052870 3000233 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyISP transmembrane anchor 8052868 3000753 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyISP domain 8052870 3000233 SCOP2B (2022-06-29)
LSCOP2 FamilyTAT signal-like 8044808 4004149 SCOP2 (2022-06-29)
LSCOP2 FamilyRieske iron-sulfur protein (ISP) 8052869 4001667 SCOP2 (2022-06-29)
LSCOP2 SuperfamilyISP transmembrane anchor 8052868 3000753 SCOP2 (2022-06-29)
LSCOP2 SuperfamilyISP domain 8052870 3000233 SCOP2 (2022-06-29)
ISCOP2B SuperfamilyISP domain 8052870 3000233 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyISP transmembrane anchor 8052868 3000753 SCOP2B (2022-06-29)
OSCOP2B SuperfamilyISP transmembrane anchor 8052868 3000753 SCOP2B (2022-06-29)
OSCOP2B SuperfamilyISP domain 8052870 3000233 SCOP2B (2022-06-29)
RSCOP2B SuperfamilyISP transmembrane anchor 8052868 3000753 SCOP2B (2022-06-29)
RSCOP2B SuperfamilyISP domain 8052870 3000233 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
PCytochrom_B_Ce2qjyP3 A: alpha bundlesX: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)H: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)T: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)F: Cytochrom_B_CECOD (1.6)
PCytochrome_Be2qjyP2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: Cytochrome_BECOD (1.6)
ACytochrom_B_Ce2qjyA3 A: alpha bundlesX: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)H: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)T: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)F: Cytochrom_B_CECOD (1.6)
ACytochrome_Be2qjyA2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: Cytochrome_BECOD (1.6)
DCytochrom_B_Ce2qjyD3 A: alpha bundlesX: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)H: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)T: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)F: Cytochrom_B_CECOD (1.6)
DCytochrome_Be2qjyD2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: Cytochrome_BECOD (1.6)
GCytochrom_B_Ce2qjyG3 A: alpha bundlesX: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)H: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)T: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)F: Cytochrom_B_CECOD (1.6)
GCytochrome_Be2qjyG2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: Cytochrome_BECOD (1.6)
JCytochrom_B_Ce2qjyJ3 A: alpha bundlesX: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)H: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)T: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)F: Cytochrom_B_CECOD (1.6)
JCytochrome_Be2qjyJ2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: Cytochrome_BECOD (1.6)
MCytochrom_B_Ce2qjyM3 A: alpha bundlesX: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)H: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) (From Topology)T: a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)F: Cytochrom_B_CECOD (1.6)
MCytochrome_Be2qjyM2 A: alpha bundlesX: Transmembrane heme-binding four-helical bundle (From Homology)H: Transmembrane heme-binding four-helical bundleT: Transmembrane di-heme cytochromesF: Cytochrome_BECOD (1.6)
BCytochrom_C1_Ne2qjyB1 A: alpha arraysX: Cytochrome c-likeH: Cytochrome c (From Topology)T: Cytochrome cF: Cytochrom_C1_NECOD (1.6)
HCytochrom_C1_Ne2qjyH1 A: alpha arraysX: Cytochrome c-likeH: Cytochrome c (From Topology)T: Cytochrome cF: Cytochrom_C1_NECOD (1.6)
NCytochrom_C1_Ne2qjyN1 A: alpha arraysX: Cytochrome c-likeH: Cytochrome c (From Topology)T: Cytochrome cF: Cytochrom_C1_NECOD (1.6)
ECytochrom_C1_Ne2qjyE1 A: alpha arraysX: Cytochrome c-likeH: Cytochrome c (From Topology)T: Cytochrome cF: Cytochrom_C1_NECOD (1.6)
KCytochrom_C1_Ne2qjyK1 A: alpha arraysX: Cytochrome c-likeH: Cytochrome c (From Topology)T: Cytochrome cF: Cytochrom_C1_NECOD (1.6)
QCytochrom_C1_Ne2qjyQ1 A: alpha arraysX: Cytochrome c-likeH: Cytochrome c (From Topology)T: Cytochrome cF: Cytochrom_C1_NECOD (1.6)
CRieske_cytochrome_bc1e2qjyC2 A: beta sandwichesX: ISP domain (From Topology)H: ISP domain (From Topology)T: ISP domainF: Rieske_cytochrome_bc1ECOD (1.6)
CRieske_6e2qjyC3 A: few secondary structure elementsX: Trm112p-like (From Topology)H: Trm112p-like (From Topology)T: Trm112p-likeF: Rieske_6ECOD (1.6)
CUCR_Fe-S_Ne2qjyC1 A: extended segmentsX: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)H: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)T: iron-sulfur subunit (ISP) transmembrane anchorF: UCR_Fe-S_NECOD (1.6)
FRieske_cytochrome_bc1e2qjyF3 A: beta sandwichesX: ISP domain (From Topology)H: ISP domain (From Topology)T: ISP domainF: Rieske_cytochrome_bc1ECOD (1.6)
FRieske_6e2qjyF4 A: few secondary structure elementsX: Trm112p-like (From Topology)H: Trm112p-like (From Topology)T: Trm112p-likeF: Rieske_6ECOD (1.6)
FUCR_Fe-S_Ne2qjyF2 A: extended segmentsX: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)H: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)T: iron-sulfur subunit (ISP) transmembrane anchorF: UCR_Fe-S_NECOD (1.6)
LRieske_cytochrome_bc1e2qjyL3 A: beta sandwichesX: ISP domain (From Topology)H: ISP domain (From Topology)T: ISP domainF: Rieske_cytochrome_bc1ECOD (1.6)
LRieske_6e2qjyL4 A: few secondary structure elementsX: Trm112p-like (From Topology)H: Trm112p-like (From Topology)T: Trm112p-likeF: Rieske_6ECOD (1.6)
LUCR_Fe-S_Ne2qjyL2 A: extended segmentsX: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)H: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)T: iron-sulfur subunit (ISP) transmembrane anchorF: UCR_Fe-S_NECOD (1.6)
IRieske_cytochrome_bc1e2qjyI4 A: beta sandwichesX: ISP domain (From Topology)H: ISP domain (From Topology)T: ISP domainF: Rieske_cytochrome_bc1ECOD (1.6)
IRieske_6e2qjyI3 A: few secondary structure elementsX: Trm112p-like (From Topology)H: Trm112p-like (From Topology)T: Trm112p-likeF: Rieske_6ECOD (1.6)
IUCR_Fe-S_Ne2qjyI2 A: extended segmentsX: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)H: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)T: iron-sulfur subunit (ISP) transmembrane anchorF: UCR_Fe-S_NECOD (1.6)
ORieske_cytochrome_bc1e2qjyO4 A: beta sandwichesX: ISP domain (From Topology)H: ISP domain (From Topology)T: ISP domainF: Rieske_cytochrome_bc1ECOD (1.6)
ORieske_6e2qjyO3 A: few secondary structure elementsX: Trm112p-like (From Topology)H: Trm112p-like (From Topology)T: Trm112p-likeF: Rieske_6ECOD (1.6)
OUCR_Fe-S_Ne2qjyO2 A: extended segmentsX: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)H: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)T: iron-sulfur subunit (ISP) transmembrane anchorF: UCR_Fe-S_NECOD (1.6)
RRieske_cytochrome_bc1e2qjyR4 A: beta sandwichesX: ISP domain (From Topology)H: ISP domain (From Topology)T: ISP domainF: Rieske_cytochrome_bc1ECOD (1.6)
RRieske_6e2qjyR3 A: few secondary structure elementsX: Trm112p-like (From Topology)H: Trm112p-like (From Topology)T: Trm112p-likeF: Rieske_6ECOD (1.6)
RUCR_Fe-S_Ne2qjyR2 A: extended segmentsX: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)H: iron-sulfur subunit (ISP) transmembrane anchor (From Topology)T: iron-sulfur subunit (ISP) transmembrane anchorF: UCR_Fe-S_NECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
P1.20.810.10 Mainly Alpha Up-down Bundle Cytochrome Bc1 Complex Chain CCATH (4.3.0)
A1.20.810.10 Mainly Alpha Up-down Bundle Cytochrome Bc1 Complex Chain CCATH (4.3.0)
D1.20.810.10 Mainly Alpha Up-down Bundle Cytochrome Bc1 Complex Chain CCATH (4.3.0)
G1.20.810.10 Mainly Alpha Up-down Bundle Cytochrome Bc1 Complex Chain CCATH (4.3.0)
J1.20.810.10 Mainly Alpha Up-down Bundle Cytochrome Bc1 Complex Chain CCATH (4.3.0)
M1.20.810.10 Mainly Alpha Up-down Bundle Cytochrome Bc1 Complex Chain CCATH (4.3.0)
B1.10.760.10 Mainly Alpha Orthogonal Bundle Cytochrome Bc1 Complex Chain D, domain 2CATH (4.3.0)
B1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
H1.10.760.10 Mainly Alpha Orthogonal Bundle Cytochrome Bc1 Complex Chain D, domain 2CATH (4.3.0)
H1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
N1.10.760.10 Mainly Alpha Orthogonal Bundle Cytochrome Bc1 Complex Chain D, domain 2CATH (4.3.0)
N1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
E1.10.760.10 Mainly Alpha Orthogonal Bundle Cytochrome Bc1 Complex Chain D, domain 2CATH (4.3.0)
E1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
K1.10.760.10 Mainly Alpha Orthogonal Bundle Cytochrome Bc1 Complex Chain D, domain 2CATH (4.3.0)
K1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
Q1.10.760.10 Mainly Alpha Orthogonal Bundle Cytochrome Bc1 Complex Chain D, domain 2CATH (4.3.0)
Q1.20.5.100 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Cytochrome c1, transmembrane anchor, C-terminalCATH (4.3.0)
C1.20.5.510 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
C2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domainCATH (4.3.0)
F1.20.5.510 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
F2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domainCATH (4.3.0)
L1.20.5.510 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
L2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domainCATH (4.3.0)
I1.20.5.510 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
I2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domainCATH (4.3.0)
O1.20.5.510 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
O2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domainCATH (4.3.0)
R1.20.5.510 Mainly Alpha Up-down Bundle Single alpha-helices involved in coiled-coils or other helix-helix interfaces Single helix binCATH (4.3.0)
R2.102.10.10 Mainly Beta 3-layer Sandwich Rieske Iron-sulfur Protein Rieske [2Fe-2S] iron-sulphur domainCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, D, G, J, M
PF00032Cytochrome b(C-terminal)/b6/petD (Cytochrom_B_C)Cytochrome b(C-terminal)/b6/petD- Domain
A, D, G, J, M
PF00033Cytochrome b/b6/petB (Cytochrome_B)Cytochrome b/b6/petB- Domain
B, E, H, K, N
PF02167Cytochrome C1 family (Cytochrom_C1)Cytochrome C1 family- Family
C, F, I, L, O
PF00355Rieske [2Fe-2S] domain (Rieske)Rieske [2Fe-2S] domainThe rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in ...The rieske domain has a [2Fe-2S] centre. Two conserved cysteines coordinate one Fe ion, while the other Fe ion is coordinated by two conserved histidines. In hyperthermophilic archaea there is a SKTPCX(2-3)C motif at the C-terminus. The cysteines in this motif form a disulphide bridge, which stabilises the protein [4].
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, D, G, J, M
Cytochrome b
B, E, H, K, N
Cytochrome c1 -
C, F, I, L, O
Ubiquinol-cytochrome c reductase iron-sulfur subunit -

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, D, G, J, M
IPR036150Cytochrome b/b6, C-terminal domain superfamilyHomologous Superfamily
A, D, G, J, M
IPR027387Cytochrome b/b6-like domain superfamilyHomologous Superfamily
A, D, G, J, M
IPR048260Cytochrome b/b6, C-terminal domain, eukaryotic/bacterialDomain
A, D, G, J, M
IPR016174Di-haem cytochrome, transmembraneHomologous Superfamily
A, D, G, J, M
IPR005798Cytochrome b/b6, C-terminalDomain
A, D, G, J, M
IPR048259Cytochrome b/b6, N-terminal domain, eukaryotic/bacterialDomain
A, D, G, J, M
IPR030689Cytochrome bFamily
A, D, G, J, M
IPR005797Cytochrome b/b6, N-terminal domainDomain
B, E, H, K, N
IPR036909Cytochrome c-like domain superfamilyHomologous Superfamily
B, E, H, K, N
IPR002326Cytochrome c1Family
B, E, H, K, N
IPR009056Cytochrome c-like domainDomain
C, F, I, L, O
IPR017941Rieske [2Fe-2S] iron-sulphur domainDomain
C, F, I, L, O
IPR005805Rieske iron-sulphur protein, C-terminalDomain
C, F, I, L, O
IPR036922Rieske [2Fe-2S] iron-sulphur domain superfamilyHomologous Superfamily
C, F, I, L, O
IPR006311Twin-arginine translocation pathway, signal sequenceConserved Site
C, F, I, L, O
IPR014349Rieske iron-sulphur proteinFamily
C, F, I, L, O
IPR019470Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signalDomain
C, F, I, L, O
IPR006317Ubiquinol-cytochrome c reductase, iron-sulphur subunitDomain
C, F, I, L, O
IPR019546Twin-arginine translocation pathway, signal sequence, bacterial/archaealConserved Site

Membrane Protein Annotation: OPM OPM Database Homepage

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
PDBTMAnnotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
MemProtMDAnnotated as membrane protein by MemProtMD