2PNR
Crystal Structure of the asymmetric Pdk3-l2 Complex
External Resource: Annotation
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
A | SCOP2B Superfamily | GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like | 8032470 | 3000091 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | alpha-ketoacid dehydrogenase kinase, N-terminal domain | 8032469 | 3001773 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like | 8032470 | 3000091 | SCOP2B (2022-06-29) |
B | SCOP2B Superfamily | alpha-ketoacid dehydrogenase kinase, N-terminal domain | 8032469 | 3001773 | SCOP2B (2022-06-29) |
D [auth E] | SCOP2B Superfamily | alpha-ketoacid dehydrogenase kinase, N-terminal domain | 8032469 | 3001773 | SCOP2B (2022-06-29) |
D [auth E] | SCOP2B Superfamily | GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like | 8032470 | 3000091 | SCOP2B (2022-06-29) |
E [auth F] | SCOP2B Superfamily | alpha-ketoacid dehydrogenase kinase, N-terminal domain | 8032469 | 3001773 | SCOP2B (2022-06-29) |
E [auth F] | SCOP2B Superfamily | GHKL (Gyrase, Hsp90, Histidine Kinase, MutL) domain-like | 8032470 | 3000091 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | BCDHK_Adom3 | e2pnrA1 | A: alpha bundles | X: Bromodomain-like | H: alpha-ketoacid dehydrogenase kinase-N (From Topology) | T: alpha-ketoacid dehydrogenase kinase-N | F: BCDHK_Adom3 | ECOD (1.6) |
A | HATPase_c | e2pnrA2 | A: a+b two layers | X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like | H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology) | T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | F: HATPase_c | ECOD (1.6) |
B | BCDHK_Adom3 | e2pnrB3 | A: alpha bundles | X: Bromodomain-like | H: alpha-ketoacid dehydrogenase kinase-N (From Topology) | T: alpha-ketoacid dehydrogenase kinase-N | F: BCDHK_Adom3 | ECOD (1.6) |
B | HATPase_c | e2pnrB4 | A: a+b two layers | X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like | H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology) | T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | F: HATPase_c | ECOD (1.6) |
D [auth E] | BCDHK_Adom3 | e2pnrE1 | A: alpha bundles | X: Bromodomain-like | H: alpha-ketoacid dehydrogenase kinase-N (From Topology) | T: alpha-ketoacid dehydrogenase kinase-N | F: BCDHK_Adom3 | ECOD (1.6) |
D [auth E] | HATPase_c | e2pnrE2 | A: a+b two layers | X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like | H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology) | T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | F: HATPase_c | ECOD (1.6) |
E [auth F] | BCDHK_Adom3 | e2pnrF3 | A: alpha bundles | X: Bromodomain-like | H: alpha-ketoacid dehydrogenase kinase-N (From Topology) | T: alpha-ketoacid dehydrogenase kinase-N | F: BCDHK_Adom3 | ECOD (1.6) |
E [auth F] | HATPase_c | e2pnrF4 | A: a+b two layers | X: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase-like | H: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase (From Topology) | T: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | F: HATPase_c | ECOD (1.6) |
C | Biotin_lipoyl | e2pnrC1 | A: a+b complex topology | X: alpha/beta-Hammerhead/Barrel-sandwich hybrid | H: alpha/beta-Hammerhead/Barrel-sandwich hybrid | T: Single hybrid motif | F: Biotin_lipoyl | ECOD (1.6) |
F [auth G] | Biotin_lipoyl | e2pnrG1 | A: a+b complex topology | X: alpha/beta-Hammerhead/Barrel-sandwich hybrid | H: alpha/beta-Hammerhead/Barrel-sandwich hybrid | T: Single hybrid motif | F: Biotin_lipoyl | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
A, B, D [auth E], E [auth F] | PF02518 | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) | Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | This family represents the structurally related ATPase domains of histidine kinase, DNA gyrase B and HSP90. | Domain |
A, B, D [auth E], E [auth F] | PF10436 | Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase (BCDHK_Adom3) | Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase | - | Family |