2ERV | pdb_00002erv

Crystal structure of the outer membrane enzyme PagL

External Resource: Annotation

Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification
Membrane Protein Annotation: OPM
Membrane Protein Annotation: PDBTM
Membrane Protein Annotation: MemProtMD
Membrane Protein Annotation: mpstruc

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	PagL-like	8044814	4004152	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	OMPA barrel-like	8053168	3000208	SCOP2 (2022-06-29)
B	SCOP2B Superfamily	OMPA barrel-like	8053168	3000208	SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	PagL	e2ervA1	A: beta barrels	X: Outer membrane meander beta-barrels	H: OMPA-like (From Topology)	T: OMPA-like	F: PagL	ECOD (1.6)
B	PagL	e2ervB1	A: beta barrels	X: Outer membrane meander beta-barrels	H: OMPA-like (From Topology)	T: OMPA-like	F: PagL	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	2.40.160.20	Mainly Beta	Beta Barrel	Porin		CATH (4.3.0)
B	2.40.160.20	Mainly Beta	Beta Barrel	Porin		CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A, B	PF09411	Lipid A 3-O-deacylase (PagL) (PagL)	Lipid A 3-O-deacylase (PagL)	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A, B	hypothetical protein Paer03002360	identical protein binding protein binding binding protein homodimerization activity protein dimerization activity hydrolase activity, acting on ester bonds carboxylic ester hydrolase activity hydrolase activity acyloxyacyl hydrolase activity catalytic activity	membrane lipid metabolic process lipooligosaccharide metabolic process glycolipid metabolic process liposaccharide metabolic process carbohydrate derivative metabolic process primary metabolic process phospholipid metabolic process lipid A metabolic process organophosphate metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process lipid metabolic process membrane lipid metabolic process lipooligosaccharide metabolic process glycolipid metabolic process liposaccharide metabolic process carbohydrate derivative metabolic process primary metabolic process phospholipid metabolic process lipid A metabolic process organophosphate metabolic process phosphate-containing compound metabolic process metabolic process cellular process phosphorus metabolic process lipid metabolic process lipopolysaccharide metabolic process macromolecule metabolic process	cellular anatomical structure membrane cell periphery cell outer membrane external encapsulating structure cell envelope outer membrane

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A, B	IPR011250	Outer membrane protein/outer membrane enzyme PagP, beta-barrel	Homologous Superfamily
A, B	IPR018550	Lipid A 3-O-deacylase-related	Family

Membrane Protein Annotation: OPM OPM Database Homepage

Chains	External Link	Type	Class	Superfamily	Family
A, B	OPM	Transmembrane	Beta-barrel transmembrane	Lipid A 3-O-deacylase (PagL) (n=8,S=10)	Lipid A 3-O-deacylase (PagL)

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

Chains	External Link	Comment
A, B	PDBTM	Annotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

Chains	External Link	Comment
A, B	MemProtMD	Annotated as membrane protein by MemProtMD

Membrane Protein Annotation: mpstruc mpstruc Database Homepage

Chains	Resource Link	Group	Subgroup	Protein
A, B	mpstruc	TRANSMEMBRANE PROTEINS: BETA-BARREL	Beta-Barrel Membrane Proteins: Monomeric/Dimeric	PagL LPS 3-O-deacylase

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.