Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Nd2einn_ Membrane and cell surface proteins and peptides Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit I-like automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Ad2eina_ Membrane and cell surface proteins and peptides Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit I-like automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Bd2einb1 All beta proteins Cupredoxin-like Cupredoxins Periplasmic domain of cytochrome c oxidase subunit II Cytochrome c oxidase (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Bd2einb2 Membrane and cell surface proteins and peptides Transmembrane helix hairpin Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c oxidase subunit II-like, transmembrane region Mitochondrial cytochrome c oxidase, subunit II (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Od2eino1 All beta proteins Cupredoxin-like Cupredoxins Periplasmic domain of cytochrome c oxidase subunit II Cytochrome c oxidase (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Od2eino2 Membrane and cell surface proteins and peptides Transmembrane helix hairpin Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c oxidase subunit II-like, transmembrane region Mitochondrial cytochrome c oxidase, subunit II (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Cd2einc_ Membrane and cell surface proteins and peptides Cytochrome c oxidase subunit III-like Cytochrome c oxidase subunit III-like Cytochrome c oxidase subunit III-like Mitochondrial cytochrome c oxidase, subunit III (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Pd2einp_ Membrane and cell surface proteins and peptides Cytochrome c oxidase subunit III-like Cytochrome c oxidase subunit III-like Cytochrome c oxidase subunit III-like Mitochondrial cytochrome c oxidase, subunit III (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Dd2eind_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit IV Mitochondrial cytochrome c oxidase subunit IV automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Qd2einq_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit IV Mitochondrial cytochrome c oxidase subunit IV automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Ed2eine_ All alpha proteins alpha-alpha superhelix Cytochrome c oxidase subunit E Cytochrome c oxidase subunit E Cytochrome c oxidase subunit E (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Rd2einr_ All alpha proteins alpha-alpha superhelix Cytochrome c oxidase subunit E Cytochrome c oxidase subunit E Cytochrome c oxidase subunit E (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Fd2einf_ Small proteins Rubredoxin-like Rubredoxin-like Cytochrome c oxidase Subunit F Cytochrome c oxidase Subunit F (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Sd2eins_ Small proteins Rubredoxin-like Rubredoxin-like Cytochrome c oxidase Subunit F Cytochrome c oxidase Subunit F (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Gd2eing_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIa Mitochondrial cytochrome c oxidase subunit VIa Mitochondrial cytochrome c oxidase subunit VIa (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Td2eint_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIa Mitochondrial cytochrome c oxidase subunit VIa Mitochondrial cytochrome c oxidase subunit VIa (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Hd2einh_ All alpha proteins Cytochrome c oxidase subunit h Cytochrome c oxidase subunit h Cytochrome c oxidase subunit h automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Ud2einu_ All alpha proteins Cytochrome c oxidase subunit h Cytochrome c oxidase subunit h Cytochrome c oxidase subunit h automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Vd2einv_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIc Mitochondrial cytochrome c oxidase subunit VIc Mitochondrial cytochrome c oxidase subunit VIc (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Id2eini_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIc Mitochondrial cytochrome c oxidase subunit VIc Mitochondrial cytochrome c oxidase subunit VIc (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Jd2einj_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIa Mitochondrial cytochrome c oxidase subunit VIIa Mitochondrial cytochrome c oxidase subunit VIIa (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Wd2einw_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIa Mitochondrial cytochrome c oxidase subunit VIIa Mitochondrial cytochrome c oxidase subunit VIIa (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Kd2eink_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIb Mitochondrial cytochrome c oxidase subunit VIIb automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Xd2einx_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIb Mitochondrial cytochrome c oxidase subunit VIIb automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Ld2einl_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Yd2einy_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Md2einm_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)
Zd2einz_ Membrane and cell surface proteins and peptides Single transmembrane helix Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) automated matches (Bos taurus ) [TaxId: 9913 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
NSCOP2B SuperfamilyCytochrome c oxidase subunit I-like 8035426 3000653 SCOP2B (2022-06-29)
ASCOP2B SuperfamilyCytochrome c oxidase subunit I-like 8035426 3000653 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyCupredoxins 8035427 3000886 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyCytochrome c oxidase subunit II-like, transmembrane region 8035428 3000692 SCOP2B (2022-06-29)
OSCOP2B SuperfamilyCytochrome c oxidase subunit II-like, transmembrane region 8035428 3000692 SCOP2B (2022-06-29)
OSCOP2B SuperfamilyCupredoxins 8035427 3000886 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyCytochrome c oxidase subunit III-like 8035429 3000671 SCOP2B (2022-06-29)
PSCOP2B SuperfamilyCytochrome c oxidase subunit III-like 8035429 3000671 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit IV 8035430 3000582 SCOP2B (2022-06-29)
QSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit IV 8035430 3000582 SCOP2B (2022-06-29)
ESCOP2B SuperfamilyCytochrome c oxidase subunit E 8035431 3001402 SCOP2B (2022-06-29)
RSCOP2B SuperfamilyCytochrome c oxidase subunit E 8035431 3001402 SCOP2B (2022-06-29)
FSCOP2B SuperfamilyRubredoxin-like 8035432 3001257 SCOP2B (2022-06-29)
SSCOP2B SuperfamilyRubredoxin-like 8035432 3001257 SCOP2B (2022-06-29)
GSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIa 8035433 3000592 SCOP2B (2022-06-29)
TSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIa 8035433 3000592 SCOP2B (2022-06-29)
HSCOP2B SuperfamilyCytochrome c oxidase subunit h 8035435 3000395 SCOP2B (2022-06-29)
USCOP2B SuperfamilyCytochrome c oxidase subunit h 8035435 3000395 SCOP2B (2022-06-29)
VSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIc 8035437 3000598 SCOP2B (2022-06-29)
ISCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIc 8035437 3000598 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIa 8035438 3000606 SCOP2B (2022-06-29)
WSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIa 8035438 3000606 SCOP2B (2022-06-29)
KSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIb 8035440 3000613 SCOP2B (2022-06-29)
XSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIb 8035440 3000613 SCOP2B (2022-06-29)
LSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) 8035441 3000624 SCOP2B (2022-06-29)
YSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) 8035441 3000624 SCOP2B (2022-06-29)
MSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIIb (aka IX) 8035443 3000633 SCOP2B (2022-06-29)
ZSCOP2B SuperfamilyMitochondrial cytochrome c oxidase subunit VIIIb (aka IX) 8035443 3000633 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
NCOX1e2einN1 A: alpha superhelicesX: Cytochrome c oxidase subunit I-likeH: Cytochrome c oxidase subunit I-like (From Topology)T: Cytochrome c oxidase subunit I-likeF: COX1ECOD (1.6)
ACOX1e2einA1 A: alpha superhelicesX: Cytochrome c oxidase subunit I-likeH: Cytochrome c oxidase subunit I-like (From Topology)T: Cytochrome c oxidase subunit I-likeF: COX1ECOD (1.6)
BCOX2e2einB1 A: beta sandwichesX: Cupredoxin-likeH: Cupredoxin-related (From Topology)T: Cupredoxin-relatedF: COX2ECOD (1.6)
BCOX2_TMe2einB2 A: extended segmentsX: Cytochrome c oxidase subunit II-like, transmembrane region (From Topology)H: Cytochrome c oxidase subunit II-like, transmembrane region (From Topology)T: Cytochrome c oxidase subunit II-like, transmembrane regionF: COX2_TMECOD (1.6)
OCOX2e2einO1 A: beta sandwichesX: Cupredoxin-likeH: Cupredoxin-related (From Topology)T: Cupredoxin-relatedF: COX2ECOD (1.6)
OCOX2_TMe2einO2 A: extended segmentsX: Cytochrome c oxidase subunit II-like, transmembrane region (From Topology)H: Cytochrome c oxidase subunit II-like, transmembrane region (From Topology)T: Cytochrome c oxidase subunit II-like, transmembrane regionF: COX2_TMECOD (1.6)
CCOX3e2einC1 A: alpha bundlesX: Cytochrome c oxidase subunit III-like (From Topology)H: Cytochrome c oxidase subunit III-like (From Topology)T: Cytochrome c oxidase subunit III-likeF: COX3ECOD (1.6)
PCOX3e2einP1 A: alpha bundlesX: Cytochrome c oxidase subunit III-like (From Topology)H: Cytochrome c oxidase subunit III-like (From Topology)T: Cytochrome c oxidase subunit III-likeF: COX3ECOD (1.6)
DCOX4e2einD1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit IV (From Topology)H: Mitochondrial cytochrome c oxidase subunit IV (From Topology)T: Mitochondrial cytochrome c oxidase subunit IVF: COX4ECOD (1.6)
QCOX4e2einQ1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit IV (From Topology)H: Mitochondrial cytochrome c oxidase subunit IV (From Topology)T: Mitochondrial cytochrome c oxidase subunit IVF: COX4ECOD (1.6)
ECOX5Ae2einE1 A: alpha superhelicesX: Repetitive alpha hairpinsH: Cytochrome c oxidase subunit E (From Topology)T: Cytochrome c oxidase subunit EF: COX5AECOD (1.6)
RCOX5Ae2einR1 A: alpha superhelicesX: Repetitive alpha hairpinsH: Cytochrome c oxidase subunit E (From Topology)T: Cytochrome c oxidase subunit EF: COX5AECOD (1.6)
FCOX5Be2einF1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Cytochrome c oxidase Subunit FF: COX5BECOD (1.6)
SCOX5Be2einS1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Cytochrome c oxidase Subunit FF: COX5BECOD (1.6)
GCOX6Ae2einG1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIa (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIa (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIaF: COX6AECOD (1.6)
TCOX6Ae2einT1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIa (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIa (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIaF: COX6AECOD (1.6)
HCOX6Be2einH1 A: few secondary structure elementsX: Cytochrome c oxidase subunit h (From Topology)H: Cytochrome c oxidase subunit h (From Topology)T: Cytochrome c oxidase subunit hF: COX6BECOD (1.6)
UCOX6Be2einU1 A: few secondary structure elementsX: Cytochrome c oxidase subunit h (From Topology)H: Cytochrome c oxidase subunit h (From Topology)T: Cytochrome c oxidase subunit hF: COX6BECOD (1.6)
VCOX6Ce2einV1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIc (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIc (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIcF: COX6CECOD (1.6)
ICOX6Ce2einI1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIc (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIc (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIcF: COX6CECOD (1.6)
JCOX7ae2einJ1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIa (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIa (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIaF: COX7aECOD (1.6)
WCOX7ae2einW1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIa (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIa (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIaF: COX7aECOD (1.6)
KCOX7Be2einK1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIb (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIb (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIbF: COX7BECOD (1.6)
XCOX7Be2einX1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIb (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIb (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIbF: COX7BECOD (1.6)
LCOX7Ce2einL1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)F: COX7CECOD (1.6)
YCOX7Ce2einY1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa) (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIc (aka VIIIa)F: COX7CECOD (1.6)
MCOX8e2einM1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX)F: COX8ECOD (1.6)
ZCOX8e2einZ1 A: extended segmentsX: Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) (From Topology)H: Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX) (From Topology)T: Mitochondrial cytochrome c oxidase subunit VIIIb (aka IX)F: COX8ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
N1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase Chain ACATH (4.3.0)
A1.20.210.10 Mainly Alpha Up-down Bundle Cytochrome C Oxidase Chain ACATH (4.3.0)
B1.10.287.90 Mainly Alpha Orthogonal Bundle Helix Hairpins CATH (4.3.0)
B2.60.40.420 Mainly Beta Sandwich Immunoglobulin-like Cupredoxins - blue copper proteinsCATH (4.3.0)
O1.10.287.90 Mainly Alpha Orthogonal Bundle Helix Hairpins CATH (4.3.0)
O2.60.40.420 Mainly Beta Sandwich Immunoglobulin-like Cupredoxins - blue copper proteinsCATH (4.3.0)
C1.10.287.70 Mainly Alpha Orthogonal Bundle Helix Hairpins CATH (4.3.0)
C1.20.120.80 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Cytochrome c oxidase, subunit III, four-helix bundleCATH (4.3.0)
P1.10.287.70 Mainly Alpha Orthogonal Bundle Helix Hairpins CATH (4.3.0)
P1.20.120.80 Mainly Alpha Up-down Bundle Four Helix Bundle (Hemerythrin (Met), subunit A) Cytochrome c oxidase, subunit III, four-helix bundleCATH (4.3.0)
D1.10.442.10 Mainly Alpha Orthogonal Bundle Cytochrome C Oxidase Chain DCATH (4.3.0)
Q1.10.442.10 Mainly Alpha Orthogonal Bundle Cytochrome C Oxidase Chain DCATH (4.3.0)
E1.25.40.40 Mainly Alpha Alpha Horseshoe Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat Cytochrome c oxidase, subunit Va/VICATH (4.3.0)
R1.25.40.40 Mainly Alpha Alpha Horseshoe Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat Cytochrome c oxidase, subunit Va/VICATH (4.3.0)
F2.60.11.10 Mainly Beta Sandwich Cytochrome C Oxidase Chain FCATH (4.3.0)
S2.60.11.10 Mainly Beta Sandwich Cytochrome C Oxidase Chain FCATH (4.3.0)
G4.10.95.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain GCATH (4.3.0)
T4.10.95.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain GCATH (4.3.0)
H1.10.10.140 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Cytochrome c oxidase, subunit VIbCATH (4.3.0)
U1.10.10.140 Mainly Alpha Orthogonal Bundle Arc Repressor Mutant, subunit A Cytochrome c oxidase, subunit VIbCATH (4.3.0)
V4.10.93.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain ICATH (4.3.0)
I4.10.93.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain ICATH (4.3.0)
J4.10.91.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain JCATH (4.3.0)
W4.10.91.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain JCATH (4.3.0)
K4.10.51.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain KCATH (4.3.0)
X4.10.51.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain KCATH (4.3.0)
L4.10.49.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain LCATH (4.3.0)
Y4.10.49.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain LCATH (4.3.0)
M4.10.81.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain MCATH (4.3.0)
Z4.10.81.10 Few Secondary Structures Irregular Cytochrome C Oxidase Chain MCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, N
PF00115Cytochrome C and Quinol oxidase polypeptide I (COX1)Cytochrome C and Quinol oxidase polypeptide I- Family
B, O
PF00116Cytochrome C oxidase subunit II, periplasmic domain (COX2)Cytochrome C oxidase subunit II, periplasmic domain- Domain
B, O
PF02790Cytochrome C oxidase subunit II, transmembrane domain (COX2_TM)Cytochrome C oxidase subunit II, transmembrane domain- Family
C, P
PF00510Cytochrome c oxidase subunit III (COX3)Cytochrome c oxidase subunit III- Family
D, Q
PF02936Cytochrome c oxidase subunit IV (COX4)Cytochrome c oxidase subunit IV- Family
F, S
PF01215Cytochrome c oxidase subunit Vb (COX5B)Cytochrome c oxidase subunit Vb- Domain
G, T
PF02046Cytochrome c oxidase subunit VIa (COX6A)Cytochrome c oxidase subunit VIa- Family
H, U
PF02297Cytochrome oxidase c subunit VIb (COX6B)Cytochrome oxidase c subunit VIbCytochrome c oxidase, a 13 sub-unit complex, EC:1.9.3.1 is the terminal oxidase in the mitochondrial electron transport chain. This family is composed of the potentially heme-binding subunit IVb of the oxidase.Domain
I, V
PF02937Cytochrome c oxidase subunit VIc (COX6C)Cytochrome c oxidase subunit VIc- Family
J, W
PF02238Cytochrome c oxidase subunit VII (COX7a)Cytochrome c oxidase subunit VII- Family
M, Z
PF02285Cytochrome oxidase c subunit VIII (COX8)Cytochrome oxidase c subunit VIII- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, N
Cytochrome c oxidase subunit 1
B, O
Cytochrome c oxidase subunit 2
C, P
Cytochrome c oxidase subunit 3
D, Q
Cytochrome c oxidase subunit 4 isoform 1
E, R
Cytochrome c oxidase polypeptide Va
F, S
Cytochrome c oxidase polypeptide Vb
G, T
Cytochrome c oxidase polypeptide VIa-heart
H, U
Cytochrome c oxidase subunit VIb isoform 1-
I, V
Cytochrome c oxidase polypeptide VIc-
J, W
Cytochrome c oxidase polypeptide VIIa-heart
K, X
Cytochrome c oxidase polypeptide VIIb-
L, Y
Cytochrome c oxidase polypeptide VIIc-
M, Z
Cytochrome c oxidase polypeptide VIII-heart-

InterPro: Protein Family Classification InterPro Database Homepage

ChainsAccessionNameType
A, N
IPR036927Cytochrome c oxidase-like, subunit I superfamilyHomologous Superfamily
A, N
IPR000883Cytochrome c oxidase subunit IFamily
A, N
IPR023615Cytochrome c oxidase, subunit I, copper-binding siteBinding Site
A, N
IPR023616Cytochrome c oxidase-like, subunit I domainDomain
A, N
IPR033944Cytochrome c oxidase subunit I domainDomain
B, O
IPR011759Cytochrome C oxidase subunit II, transmembrane domainDomain
B, O
IPR036257Cytochrome C oxidase subunit II, transmembrane domain superfamilyHomologous Superfamily
B, O
IPR034210Cytochrome c oxidase subunit 2, C-terminalDomain
B, O
IPR045187Cytochrome c/quinol oxidase subunit IIFamily
B, O
IPR002429Cytochrome c oxidase subunit II-like C-terminalDomain
B, O
IPR008972CupredoxinHomologous Superfamily
B, O
IPR001505Copper centre Cu(A)Binding Site
B, O
IPR014222Cytochrome c oxidase, subunit IIDomain
C, P
IPR035973Cytochrome c oxidase subunit III-like superfamilyHomologous Superfamily
C, P
IPR013833Cytochrome c oxidase, subunit III, 4-helical bundleHomologous Superfamily
C, P
IPR000298Cytochrome c oxidase subunit III-likeDomain
C, P
IPR033945Cytochrome c oxidase subunit III domainDomain
C, P
IPR024791Cytochrome c oxidase subunit IIIFamily
D, Q
IPR004203Cytochrome c oxidase subunit IV familyFamily
D, Q
IPR013288Cytochrome c oxidase subunit IVFamily
D, Q
IPR036639Cytochrome c oxidase subunit IV superfamilyHomologous Superfamily
E, R
IPR003204Cytochrome c oxidase, subunit Va/VIFamily
E, R
IPR036545Cytochrome c oxidase, subunit Va/VI superfamilyHomologous Superfamily
F, S
IPR002124Cytochrome c oxidase, subunit VbFamily
F, S
IPR036972Cytochrome c oxidase, subunit Vb superfamilyHomologous Superfamily
G, T
IPR018507Cytochrome c oxidase, subunit VIa, conserved siteConserved Site
G, T
IPR036418Cytochrome c oxidase, subunit VIa superfamilyHomologous Superfamily
G, T
IPR001349Cytochrome c oxidase, subunit VIaFamily
H, U
IPR036549Cytochrome c oxidase subunit 6B/Cytochrome c oxidase assembly factor 6-like superfamilyHomologous Superfamily
H, U
IPR048280Cytochrome oxidase c subunit VIb-likeFamily
H, U
IPR003213Cytochrome c oxidase, subunit VIbFamily
I, V
IPR037169Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamilyHomologous Superfamily
I, V
IPR051389Cytochrome c oxidase subunit VIcFamily
I, V
IPR034884Mitochondrial cytochrome c oxidase subunit VIc/VIIsFamily
J, W
IPR003177Cytochrome c oxidase subunit VIIa, metazoaFamily
J, W
IPR036539Cytochrome c oxidase, subunit VIIa superfamilyHomologous Superfamily
J, W
IPR039297Cytochrome c oxidase subunit VIIFamily
K, X
IPR023272Cytochrome C oxidase, subunit VIIB domain superfamilyHomologous Superfamily
K, X
IPR008433Cytochrome C oxidase, subunit VIIBFamily
L, Y
IPR036636Cytochrome c oxidase subunit VIIc superfamilyHomologous Superfamily
L, Y
IPR004202Cytochrome c oxidase subunit VIIcFamily
M, Z
IPR003205Cytochrome c oxidase, subunit 8Family
M, Z
IPR036548Cytochrome c oxidase, subunit 8 superfamilyHomologous Superfamily

Membrane Protein Annotation: PDBTM PDBTM Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
PDBTMAnnotated as membrane protein by PDBTM

Membrane Protein Annotation: MemProtMD MemProtMD Database Homepage

ChainsExternal LinkComment
A, B, C, D, E
MemProtMDAnnotated as membrane protein by MemProtMD

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
A, N
FME Parent Component: MET

RESIDAA0021 , AA0566

PSI-MOD :  N-formyl-L-methionine residue MOD:00030 , N-formyl-L-methionine (Met) MOD:00482 , N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet) MOD:01890 , N-[(L-histidin-1'-yl)methyl]-L-methionine (Met) MOD:01891
B, O
FME Parent Component: MET

RESIDAA0021 , AA0566 , AA0021 , AA0566

PSI-MOD :  N-formyl-L-methionine residue MOD:00030 , N-formyl-L-methionine (Met) MOD:00482 , N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet) MOD:01890 , N-[(L-histidin-1'-yl)methyl]-L-methionine (Met) MOD:01891 , N-formyl-L-methionine residue MOD:00030 , N-formyl-L-methionine (Met) MOD:00482 , N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet) MOD:01890 , N-[(L-histidin-1'-yl)methyl]-L-methionine (Met) MOD:01891
G, T
TPO Parent Component: THR

RESIDAA0021 , AA0566 , AA0021 , AA0566 , AA0038

PSI-MOD :  N-formyl-L-methionine residue MOD:00030 , N-formyl-L-methionine (Met) MOD:00482 , N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet) MOD:01890 , N-[(L-histidin-1'-yl)methyl]-L-methionine (Met) MOD:01891 , N-formyl-L-methionine residue MOD:00030 , N-formyl-L-methionine (Met) MOD:00482 , N-[(L-histidin-1'-yl)methyl]-L-methionine (fMet) MOD:01890 , N-[(L-histidin-1'-yl)methyl]-L-methionine (Met) MOD:01891 , O-phospho-L-threonine MOD:00047
I, V
SAC Parent Component: SER

RESIDAA0021 , AA0566 , AA0021 , AA0566 , AA0038