2XY5
Crystal structure of an artificial salen-copper basepair in complex with fragment DNA polymerase I from Bacillus stearothermophilus
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
A | DNA_pol_A_2nd | e2xy5A1 | A: alpha arrays | X: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology) | H: helical bundle in Bacillus stearothermophilus-like DNA polymerase I (From Topology) | T: helical bundle in Bacillus stearothermophilus-like DNA polymerase I | F: DNA_pol_A_2nd | ECOD (1.6) |
A | DNA_pol_A_1st | e2xy5A2 | A: alpha bundles | X: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology) | H: fingers domain in bacteriophage RB69-like DNA polymerase I (From Topology) | T: fingers domain in bacteriophage RB69-like DNA polymerase I | F: DNA_pol_A_1st | ECOD (1.6) |
A | DNA_pol_A_3rd | e2xy5A3 | A: a+b two layers | X: Alpha-beta plaits | H: Adenylyl and guanylyl cyclase catalytic domain-like | T: Adenylyl and guanylyl cyclase catalytic domain-like | F: DNA_pol_A_3rd | ECOD (1.6) |
A | DNA_pol_A_exo1_1 | e2xy5A4 | A: mixed a+b and a/b | X: Ribonuclease H-like | H: Ribonuclease H-like (From Topology) | T: Ribonuclease H-like | F: DNA_pol_A_exo1_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
A | 3.30.420.10 | Alpha Beta | 2-Layer Sandwich | Nucleotidyltransferase | domain 5 | CATH (4.3.0) |
A | 1.20.1060.10 | Mainly Alpha | Up-down Bundle | Taq DNA Polymerase | Chain T, domain 4 | CATH (4.3.0) |
A | 3.30.70.370 | Alpha Beta | 2-Layer Sandwich | Alpha-Beta Plaits | CATH (4.3.0) | |
A | 1.10.150.20 | Mainly Alpha | Orthogonal Bundle | DNA polymerase | domain 1 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF22619 | DNA polymerase I, ribonuclease H-like domain (DNA_polI_exo1) | DNA polymerase I, ribonuclease H-like domain | This domain is responsible for the 3'-5' exonuclease proofreading activity of E. coli DNA polymerase I (polI) and other related enzymes. It is one of the constituent domains of Klenow fragment. | Domain | |
PF00476 | DNA polymerase family A (DNA_pol_A) | DNA polymerase family A | - | Family | |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR036397 | Ribonuclease H superfamily | Homologous Superfamily | |
IPR043502 | DNA/RNA polymerase superfamily | Homologous Superfamily | |
IPR001098 | DNA-directed DNA polymerase, family A, palm domain | Domain | |
IPR054690 | DNA polymerase I, 3'-5' exonuclease domain | Domain | |
IPR002298 | DNA polymerase A | Family | |
IPR019760 | DNA-directed DNA polymerase, family A, conserved site | Conserved Site | |
IPR018320 | DNA polymerase 1 | Family | |
IPR012337 | Ribonuclease H-like superfamily | Homologous Superfamily | |
IPR002562 | 3'-5' exonuclease domain | Domain |