Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilyEukaryotic proteases 8031823 4000286 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyTrypsin-like serine proteases 8044201 3000114 SCOP2 (2022-06-29)
BSCOP2B SuperfamilyTrypsin-like serine proteases 8044201 3000114 SCOP2B (2022-06-29)
DSCOP2B SuperfamilyEcotin, trypsin inhibitor 8041127 3001256 SCOP2B (2022-06-29)
CSCOP2B SuperfamilyEcotin, trypsin inhibitor 8041127 3001256 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ATrypsin_1e1xx9A1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: FMN-binding split barrel 2F: Trypsin_1ECOD (1.6)
BTrypsin_1e1xx9B1 A: beta barrelsX: cradle loop barrelH: RIFT-relatedT: FMN-binding split barrel 2F: Trypsin_1ECOD (1.6)
DEcotine1xx9D1 A: beta sandwichesX: Ecotin, trypsin inhibitor (From Topology)H: Ecotin, trypsin inhibitor (From Topology)T: Ecotin, trypsin inhibitorF: EcotinECOD (1.6)
CEcotine1xx9C1 A: beta sandwichesX: Ecotin, trypsin inhibitor (From Topology)H: Ecotin, trypsin inhibitor (From Topology)T: Ecotin, trypsin inhibitorF: EcotinECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

ChainDomainClassArchitectureTopologyHomologyProvenance Source (Version)
A2.40.10.10 Mainly Beta Beta Barrel Thrombin, subunit H Trypsin-like serine proteasesCATH (4.3.0)
B2.40.10.10 Mainly Beta Beta Barrel Thrombin, subunit H Trypsin-like serine proteasesCATH (4.3.0)
D2.60.40.550 Mainly Beta Sandwich Immunoglobulin-like EcotinCATH (4.3.0)
C2.60.40.550 Mainly Beta Sandwich Immunoglobulin-like EcotinCATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B
PF00089Trypsin (Trypsin)Trypsin- Domain
C, D
PF03974Ecotin (Ecotin)Ecotin- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B
Coagulation factor XI
C, D
Ecotin