1TCV
Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d1tcvb_ | Alpha and beta proteins (a/b) | Phosphorylase/hydrolase-like | Purine and uridine phosphorylases | automated matches | automated matches | (Schistosoma mansoni ) [TaxId: 6183 ], | SCOPe (2.08) |
A | d1tcva_ | Alpha and beta proteins (a/b) | Phosphorylase/hydrolase-like | Purine and uridine phosphorylases | automated matches | automated matches | (Schistosoma mansoni ) [TaxId: 6183 ], | SCOPe (2.08) |
C | d1tcvc_ | Alpha and beta proteins (a/b) | Phosphorylase/hydrolase-like | Purine and uridine phosphorylases | automated matches | automated matches | (Schistosoma mansoni ) [TaxId: 6183 ], | SCOPe (2.08) |
Domain Annotation: SCOP2 Classification SCOP2 Database Homepage
Chains | Type | Family Name | Domain Identifier | Family Identifier | Provenance Source (Version) |
---|---|---|---|---|---|
B | SCOP2B Superfamily | Purine and uridine phosphorylases | 8061234 | 3000626 | SCOP2B (2022-06-29) |
A | SCOP2B Superfamily | Purine and uridine phosphorylases | 8061234 | 3000626 | SCOP2B (2022-06-29) |
C | SCOP2B Superfamily | Purine and uridine phosphorylases | 8061234 | 3000626 | SCOP2B (2022-06-29) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | PNP_UDP_1 | e1tcvB1 | A: a/b three-layered sandwiches | X: Phosphorylase/hydrolase-like | H: Peptidyl-tRNA hydrolase-like (From Topology) | T: Peptidyl-tRNA hydrolase-like | F: PNP_UDP_1 | ECOD (1.6) |
A | PNP_UDP_1 | e1tcvA1 | A: a/b three-layered sandwiches | X: Phosphorylase/hydrolase-like | H: Peptidyl-tRNA hydrolase-like (From Topology) | T: Peptidyl-tRNA hydrolase-like | F: PNP_UDP_1 | ECOD (1.6) |
C | PNP_UDP_1 | e1tcvC1 | A: a/b three-layered sandwiches | X: Phosphorylase/hydrolase-like | H: Peptidyl-tRNA hydrolase-like (From Topology) | T: Peptidyl-tRNA hydrolase-like | F: PNP_UDP_1 | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.50.1580 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Nucleoside phosphorylase domain | CATH (4.3.0) |
A | 3.40.50.1580 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Nucleoside phosphorylase domain | CATH (4.3.0) |
C | 3.40.50.1580 | Alpha Beta | 3-Layer(aba) Sandwich | Rossmann fold | Nucleoside phosphorylase domain | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF01048 | Phosphorylase superfamily (PNP_UDP_1) | Phosphorylase superfamily | Members of this family include: purine nucleoside phosphorylase (PNP) Uridine phosphorylase (UdRPase) 5'-methylthioadenosine phosphorylase (MTA phosphorylase) | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
Chains | Polymer | Molecular Function | Biological Process | Cellular Component |
---|---|---|---|---|
purine-nucleoside phosphorylase |
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR035994 | Nucleoside phosphorylase superfamily | Homologous Superfamily | |
IPR011268 | Purine nucleoside phosphorylase | Family | |
IPR011270 | Purine nucleoside phosphorylase I, inosine/guanosine-specific | Family | |
IPR000845 | Nucleoside phosphorylase domain | Domain |