Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

ChainsDomain InfoClassFoldSuperfamilyFamilyDomainSpeciesProvenance Source (Version)
Ad1sosa_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
B [auth F]d1sosf_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
C [auth B]d1sosb_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
D [auth G]d1sosg_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
E [auth C]d1sosc_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
G [auth D]d1sosd_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
H [auth I]d1sosi_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
I [auth E]d1sose_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
F [auth H]d1sosh_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)
Jd1sosj_ All beta proteins Immunoglobulin-like beta-sandwich Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase-like Cu,Zn superoxide dismutase, SOD human (Homo sapiens ) [TaxId: 9606 ], SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
B [auth F]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
C [auth B]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
D [auth G]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
E [auth C]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
G [auth D]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
H [auth I]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
I [auth E]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
F [auth H]SCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)
JSCOP2B SuperfamilyCu, Zn superoxide dismutase-like 8055253 3002059 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASod_Cue1sosA1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
B [auth F]Sod_Cue1sosF1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
C [auth B]Sod_Cue1sosB1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
D [auth G]Sod_Cue1sosG1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
E [auth C]Sod_Cue1sosC1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
G [auth D]Sod_Cue1sosD1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
H [auth I]Sod_Cue1sosI1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
I [auth E]Sod_Cue1sosE1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
F [auth H]Sod_Cue1sosH1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)
JSod_Cue1sosJ1 A: beta sandwichesX: Immunoglobulin-like beta-sandwichH: Immunoglobulin-relatedT: Cu,Zn superoxide dismutase-likeF: Sod_CuECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
PF00080Copper/zinc superoxide dismutase (SODC) (Sod_Cu)Copper/zinc superoxide dismutase (SODC)superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SO ...superoxide dismutases (SODs) catalyse the conversion of superoxide radicals to hydrogen peroxide and molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the human SOD1 gene cause familial amyotrophic lateral sclerosis (Lou Gehrig's disease). Structure is an eight-stranded beta sandwich, similar to the immunoglobulin fold.
Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
SUPEROXIDE DISMUTASE

Pharos: Disease Associations Pharos Homepage Annotation

ChainsDrug Target  Associated Disease
PharosP00441

Protein Modification Annotation

Modified Residue(s)
ChainResidue(s)Description
ACE RESIDAA0041 , AA0042 , AA0043 , AA0044 , AA0045 , AA0046 , AA0049 , AA0050 , AA0051 , AA0052 , AA0053 , AA0054 , AA0354

PSI-MOD :  N-acetyl-L-alanine MOD:00050 , N-acetyl-L-aspartic acid MOD:00051 , N-acetyl-L-cysteine MOD:00052 , N-acetyl-S-archeol-cysteine MOD:00897 , N-acetyl-L-glutamic acid MOD:00053 , N-acetyl-L-glutamine MOD:00054 , N-acetylglycine MOD:00055 , N-acetyl-L-methionine MOD:00058 , N-acetyl-L-proline MOD:00059 , N-acetyl-L-serine MOD:00060 , N,O-diacetylated L-serine MOD:00648 , N-acetyl-L-threonine MOD:00061 , N-acetyl-L-tyrosine MOD:00062 , N-acetyl-L-valine MOD:00063 , N2-acetyl-L-arginine MOD:00359