Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

ChainsTypeFamily Name Domain Identifier Family IdentifierProvenance Source (Version)
ASCOP2 FamilySir2 family of transcriptional regulators 8021856 4003387 SCOP2 (2022-06-29)
ASCOP2 SuperfamilyDHS-like NAD/FAD-binding domain 8034236 3001728 SCOP2 (2022-06-29)
CSCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8034236 3001728 SCOP2B (2022-06-29)
BSCOP2B SuperfamilyDHS-like NAD/FAD-binding domain 8034236 3001728 SCOP2B (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

ChainsFamily NameDomain Identifier ArchitecturePossible HomologyHomologyTopologyFamilyProvenance Source (Version)
ASIR2_1ste1j8fA2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
ASIR2_2nde1j8fA1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: SIR2_2ndECOD (1.6)
CSIR2_1ste1j8fC1 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
CSIR2_2nde1j8fC2 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: SIR2_2ndECOD (1.6)
BSIR2_1ste1j8fB2 A: a/b three-layered sandwichesX: Rossmann-likeH: Rossmann-relatedT: DHS-like NAD/FAD-binding domainF: SIR2_1stECOD (1.6)
BSIR2_2nde1j8fB1 A: few secondary structure elementsX: Rubredoxin-likeH: Rubredoxin-relatedT: Rubredoxin-relatedF: SIR2_2ndECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Protein Family Annotation Pfam Database Homepage

ChainsAccessionNameDescriptionCommentsSource
A, B, C
PF02146Sir2 family (SIR2)Sir2 family- Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

ChainsPolymerMolecular FunctionBiological ProcessCellular Component
A, B, C
SIRTUIN 2, ISOFORM 1