1HW7 | pdb_00001hw7

HSP33, HEAT SHOCK PROTEIN WITH REDOX-REGULATED CHAPERONE ACTIVITY

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
A	d1hw7a_	Alpha and beta proteins (a+b)	Hsp33 domain	Hsp33 domain	Hsp33 domain	Heat shock protein 33, Hsp33	(Escherichia coli ) [TaxId: 562 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
A	SCOP2 Family	Hsp33 domain	8020955	4003643	SCOP2 (2022-06-29)
A	SCOP2 Superfamily	Hsp33 domain	8033335	3001176	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
A	HSP33_N	e1hw7A1	A: a+b complex topology	X: Hsp33 domain (From Topology)	H: Hsp33 domain (From Topology)	T: Hsp33 domain	F: HSP33_N	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
A	3.55.30.10	Alpha Beta	3-Layer(bab) Sandwich	Hsp33 domain	Hsp33 domain	CATH (4.3.0)
A	1.10.287.480	Mainly Alpha	Orthogonal Bundle	Helix Hairpins	helix hairpin bin	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
A	PF01430	Hsp33 protein (HSP33)	Hsp33 protein	-	Family

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A	HEAT SHOCK PROTEIN HSP33	unfolded protein binding protein binding binding protein folding chaperone cation binding transition metal ion binding zinc ion binding ion binding metal ion binding small molecule binding identical protein binding	protein refolding primary metabolic process gene expression macromolecule biosynthetic process protein maturation protein folding biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process regulation of protein stability biological regulation maintenance of unfolded protein protein refolding primary metabolic process gene expression macromolecule biosynthetic process protein maturation protein folding biosynthetic process metabolic process cellular process protein metabolic process macromolecule metabolic process regulation of protein stability biological regulation maintenance of unfolded protein regulation of biological quality response to oxidative stress response to stimulus response to stress response to heat response to abiotic stimulus response to temperature stimulus	cellular anatomical structure intracellular anatomical structure cytoplasm cytosol

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
A	IPR016154	Heat shock protein Hsp33, C-terminal	Homologous Superfamily
A	IPR023212	Heat shock protein Hsp33, helix hairpin bin domain superfamily	Homologous Superfamily
A	IPR000397	Heat shock protein Hsp33	Family
A	IPR016153	Heat shock protein Hsp33, N-terminal	Homologous Superfamily

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.