1AIS | pdb_00001ais

TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI

External Resource: Annotation

Domain Annotation: SCOP/SCOPe Classification
Domain Annotation: SCOP2 Classification
Domain Annotation: ECOD Classification
Domain Annotation: CATH
Protein Family Annotation
Gene Ontology: Gene Product Annotation
InterPro: Protein Family Classification

Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage

Chains	Domain Info	Class	Fold	Superfamily	Family	Domain	Species	Provenance Source (Version)
C [auth A]	d1aisa1	Alpha and beta proteins (a+b)	TBP-like	TATA-box binding protein-like	TATA-box binding protein (TBP), C-terminal domain	TATA-box binding protein (TBP), C-terminal domain	(Pyrococcus woesei ) [TaxId: 2262 ],	SCOPe (2.08)
D [auth B]	d1aisb1	All alpha proteins	Cyclin-like	Cyclin-like	Transcription factor IIB (TFIIB), core domain	Transcription factor IIB (TFIIB), core domain	(Pyrococcus woesei ) [TaxId: 2262 ],	SCOPe (2.08)

Domain Annotation: SCOP2 Classification SCOP2 Database Homepage

Chains	Type	Family Name	Domain Identifier	Family Identifier	Provenance Source (Version)
C [auth A]	SCOP2 Family	TATA-box binding protein (TBP), C-terminal domain	8023978	4002023	SCOP2 (2022-06-29)
C [auth A]	SCOP2 Family	TATA-box binding protein (TBP), C-terminal domain	8023980	4002023	SCOP2 (2022-06-29)
C [auth A]	SCOP2 Superfamily	TATA-box binding protein-like	8036357	3000705	SCOP2 (2022-06-29)
C [auth A]	SCOP2 Superfamily	TATA-box binding protein-like	8036359	3000705	SCOP2 (2022-06-29)
D [auth B]	SCOP2 Family	Transcription factor IIB (TFIIB), core domain	8025564	4001107	SCOP2 (2022-06-29)
D [auth B]	SCOP2 Family	Transcription factor IIB (TFIIB), core domain	8025565	4001107	SCOP2 (2022-06-29)
D [auth B]	SCOP2 Superfamily	Cyclin-like	8037943	3000768	SCOP2 (2022-06-29)
D [auth B]	SCOP2 Superfamily	Cyclin-like	8037944	3000768	SCOP2 (2022-06-29)

Domain Annotation: ECOD Classification ECOD Database Homepage

Chains	Family Name	Domain Identifier	Architecture	Possible Homology	Homology	Topology	Family	Provenance Source (Version)
C [auth A]	TBP	e1aisA1	A: a+b two layers	X: TBP-like	H: TATA-box binding protein-like (From Topology)	T: TATA-box binding protein-like	F: TBP	ECOD (1.6)
D [auth B]	TFIIB	e1aisB1	A: alpha arrays	X: HTH	H: HTH	T: Cyclin-like	F: TFIIB	ECOD (1.6)

Domain Annotation: CATH CATH Database Homepage

Chain	Domain	Class	Architecture	Topology	Homology	Provenance Source (Version)
C [auth A]	3.30.310.10	Alpha Beta	2-Layer Sandwich	TATA-Binding Protein	TATA-Binding Protein	CATH (4.3.0)
D [auth B]	1.10.472.10	Mainly Alpha	Orthogonal Bundle	Cyclin A	domain 1	CATH (4.3.0)

Protein Family Annotation Pfam Database Homepage

Chains	Accession	Name	Description	Comments	Source
C [auth A]	PF00352	Transcription factor TFIID (or TATA-binding protein, TBP) (TBP)	Transcription factor TFIID (or TATA-binding protein, TBP)		Domain
D [auth B]	PF00382	Transcription factor TFIIB repeat (TFIIB)	Transcription factor TFIIB repeat		Domain

Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage

Chains	Polymer	Molecular Function	Biological Process	Cellular Component
A [auth C]	DNA (5'-D(APAPCPTPTPAPCPTPTPTP(5IU)P(5IU)PAPAPAPGP*C)-3')	-	-	-
B [auth E]	DNA (5'-D(GPCPTPTPTPAPAPAPAPAPGPTPAPAPGPTP*T )-3')	-	-	-
C [auth A]	PROTEIN (TATA-BINDING PROTEIN)	DNA binding binding nucleic acid binding transcription regulator activity DNA-binding transcription factor activity	RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process biosynthetic process metabolic process cellular process RNA metabolic process primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process biosynthetic process metabolic process cellular process macromolecule metabolic process	-
D [auth B]	PROTEIN (TRANSCRIPTION INITIATION FACTOR IIB)	transcription regulator activity DNA-binding transcription factor activity cation binding transition metal ion binding zinc ion binding ion binding binding metal ion binding small molecule binding transcription factor binding protein binding TBP-class protein binding general transcription initiation factor binding	transcription preinitiation complex assembly RNA metabolic process cellular component organization cellular component biogenesis protein-DNA complex organization RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process cellular component assembly protein-containing complex assembly cellular component organization or biogenesis protein-containing complex organization protein-DNA complex assembly transcription preinitiation complex assembly RNA metabolic process cellular component organization cellular component biogenesis protein-DNA complex organization RNA biosynthetic process nucleobase-containing compound metabolic process DNA-templated transcription nucleic acid biosynthetic process cellular component assembly protein-containing complex assembly cellular component organization or biogenesis protein-containing complex organization protein-DNA complex assembly primary metabolic process nucleobase-containing compound biosynthetic process gene expression macromolecule biosynthetic process DNA-templated transcription initiation nucleic acid metabolic process biosynthetic process cellular process metabolic process macromolecule metabolic process	transcription preinitiation complex protein-containing complex protein-DNA complex

InterPro: Protein Family Classification InterPro Database Homepage

Chains	Accession	Name	Type
C [auth A]	IPR030491	TATA-box binding protein, conserved site	Conserved Site
C [auth A]	IPR000814	TATA-box binding protein	Family
C [auth A]	IPR012295	TBP domain superfamily	Homologous Superfamily
C [auth A]	IPR033711	TATA-box binding protein, archaea	Family
D [auth B]	IPR000812	Transcription factor TFIIB	Family
D [auth B]	IPR023486	Transcription factor TFIIB, conserved site	Conserved Site
D [auth B]	IPR013137	Zinc finger, TFIIB-type	Domain
D [auth B]	IPR036915	Cyclin-like superfamily	Homologous Superfamily
D [auth B]	IPR023484	Transcription initiation factor TFIIB, archaea	Family
D [auth B]	IPR013150	Transcription factor TFIIB, cyclin-like domain	Domain
D [auth B]	IPR013763	Cyclin-like domain	Domain

RCSB PDB Core Operations are funded by the U.S. National Science Foundation (DBI-2321666), the US Department of Energy (DE-SC0019749), and the National Cancer Institute, National Institute of Allergy and Infectious Diseases, and National Institute of General Medical Sciences of the National Institutes of Health under grant R01GM157729.