1P1Q
Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with AMPA
Domain Annotation: SCOP/SCOPe Classification SCOP-e Database Homepage
Chains | Domain Info | Class | Fold | Superfamily | Family | Domain | Species | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | d1p1qb_ | Alpha and beta proteins (a/b) | Periplasmic binding protein-like II | Periplasmic binding protein-like II | Phosphate binding protein-like | Glutamate receptor ligand binding core | Norway rat (Rattus norvegicus ) [TaxId: 10116 ], Norway rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
C | d1p1qc_ | Alpha and beta proteins (a/b) | Periplasmic binding protein-like II | Periplasmic binding protein-like II | Phosphate binding protein-like | Glutamate receptor ligand binding core | Norway rat (Rattus norvegicus ) [TaxId: 10116 ], Norway rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
A | d1p1qa_ | Alpha and beta proteins (a/b) | Periplasmic binding protein-like II | Periplasmic binding protein-like II | Phosphate binding protein-like | Glutamate receptor ligand binding core | Norway rat (Rattus norvegicus ) [TaxId: 10116 ], Norway rat (Rattus norvegicus ) [TaxId: 10116 ], | SCOPe (2.08) |
Domain Annotation: ECOD Classification ECOD Database Homepage
Chains | Family Name | Domain Identifier | Architecture | Possible Homology | Homology | Topology | Family | Provenance Source (Version) |
---|---|---|---|---|---|---|---|---|
B | Lig_chan_3 | e1p1qB1 | A: a/b three-layered sandwiches | X: Periplasmic binding protein-like II (From Topology) | H: Periplasmic binding protein-like II (From Topology) | T: Periplasmic binding protein-like II | F: Lig_chan_3 | ECOD (1.6) |
B | SBP_bac_3_1st | e1p1qB2 | A: a/b three-layered sandwiches | X: Periplasmic binding protein-like II (From Topology) | H: Periplasmic binding protein-like II (From Topology) | T: Periplasmic binding protein-like II | F: SBP_bac_3_1st | ECOD (1.6) |
C | Lig_chan_3 | e1p1qC1 | A: a/b three-layered sandwiches | X: Periplasmic binding protein-like II (From Topology) | H: Periplasmic binding protein-like II (From Topology) | T: Periplasmic binding protein-like II | F: Lig_chan_3 | ECOD (1.6) |
C | SBP_bac_3_1st | e1p1qC2 | A: a/b three-layered sandwiches | X: Periplasmic binding protein-like II (From Topology) | H: Periplasmic binding protein-like II (From Topology) | T: Periplasmic binding protein-like II | F: SBP_bac_3_1st | ECOD (1.6) |
A | Lig_chan_3 | e1p1qA2 | A: a/b three-layered sandwiches | X: Periplasmic binding protein-like II (From Topology) | H: Periplasmic binding protein-like II (From Topology) | T: Periplasmic binding protein-like II | F: Lig_chan_3 | ECOD (1.6) |
A | SBP_bac_3_1st | e1p1qA1 | A: a/b three-layered sandwiches | X: Periplasmic binding protein-like II (From Topology) | H: Periplasmic binding protein-like II (From Topology) | T: Periplasmic binding protein-like II | F: SBP_bac_3_1st | ECOD (1.6) |
Domain Annotation: CATH CATH Database Homepage
Chain | Domain | Class | Architecture | Topology | Homology | Provenance Source (Version) |
---|---|---|---|---|---|---|
B | 3.40.190.10 | Alpha Beta | 3-Layer(aba) Sandwich | D-Maltodextrin-Binding Protein | domain 2 | CATH (4.3.0) |
C | 3.40.190.10 | Alpha Beta | 3-Layer(aba) Sandwich | D-Maltodextrin-Binding Protein | domain 2 | CATH (4.3.0) |
A | 3.40.190.10 | Alpha Beta | 3-Layer(aba) Sandwich | D-Maltodextrin-Binding Protein | domain 2 | CATH (4.3.0) |
Protein Family Annotation Pfam Database Homepage
Chains | Accession | Name | Description | Comments | Source |
---|---|---|---|---|---|
PF00060 | Ligand-gated ion channel (Lig_chan) | Ligand-gated ion channel | - | Family | |
PF10613 | Ligated ion channel L-glutamate- and glycine-binding site (Lig_chan-Glu_bd) | Ligated ion channel L-glutamate- and glycine-binding site | This region, sometimes called the S1 domain, is the luminal domain just upstream of the first, M1, transmembrane region of transmembrane ion-channel proteins, and it binds L-glutamate and glycine [2]. It is found in association with Lig_chan, Pfam:PF ... | Domain |
Gene Ontology: Gene Product Annotation Gene Ontology Database Homepage
InterPro: Protein Family Classification InterPro Database Homepage
Chains | Accession | Name | Type |
---|---|---|---|
IPR028082 | Periplasmic binding protein-like I | Homologous Superfamily | |
IPR001508 | Ionotropic glutamate receptor, metazoa | Family | |
IPR001828 | Receptor, ligand binding region | Domain | |
IPR001320 | Ionotropic glutamate receptor, C-terminal | Domain | |
IPR019594 | Ionotropic glutamate receptor, L-glutamate and glycine-binding domain | Domain | |
IPR015683 | Ionotropic glutamate receptor | Family |