3D View: 4GKI

  

4GKI

Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor 1-NM-PP1

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RCSB PDB Mol* Viewer 2.10.6 [10/28/2024, 3:56:31 PM]
Sequence of
0    ​G​​MSE​​S​​H​​I​​Q​​R​​E​​T​​S​10   ​C​​S​​R​​P​​R​​L​​N​​S​​N​​L​20   ​D​​A​​D​​L​​Y​​G​​Y​​R​​W​​A​30   ​R​​D​​N​​V​​G​​Q​​S​​G​​A​​T​40   ​I​​Y​​R​​L​​Y​​G​​K​​P​​N​​A​50   ​P​​E​​L​​F​​L​​K​​H​​G​​K​​G​60   ​S​​V​​A​​N​​D​​V​​T​​D​​E​​MSE​70   ​V​​R​​L​​N​​W​​L​​T​​A​​F​​MSE​80   ​P​​L​​P​​T​​I​​K​​H​​F​​I​​R​90   ​T​​P​​D​​D​​A​​W​​L​​L​​T​​T​100  ​A​​I​​P​​G​​K​​T​​A​​F​​Q​​V​110  ​L​​E​​E​​Y​​P​​D​​S​​G​​E​​N​120  ​I​​V​​D​​A​​L​​A​​V​​F​​L​​R​130  ​R​​L​​H​​S​​I​​P​​V​​C​​N​​C​140  ​P​​F​​N​​S​​D​​R​​V​​F​​R​​L​150  ​A​​Q​​A​​Q​​S​​R​​MSE​​N​​N​​G​160  ​L​​V​​D​​A​​S​​D​​F​​D​​D​​E​170  ​R​​N​​G​​W​​P​​V​​E​​Q​​V​​W​180  ​K​​E​​MSE​​H​​K​​L​​L​​P​​F​​S​190  ​P​​D​​S​​V​​V​​T​​H​​G​​D​​F​200  ​S​​L​​D​​N​​L​​I​​F​​D​​E​​G​210  ​K​​L​​I​​G​​C​​I​​D​​V​​G​​R​220  ​V​​G​​I​​A​​D​​R​​Y​​Q​​D​​L​230  ​A​​I​​L​​W​​N​​C​​L​​G​​E​​F​240  ​S​​P​​S​​L​​Q​​K​​R​​L​​F​​Q​250  ​K​​Y​​G​​I​​D​​N​​P​​D​​MSE​​N​260  ​K​​L​​Q​​F​​H​​L​​MSE​​L​​D​​E​270  ​F​​F​
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