4EA0 | pdb_00004ea0

Crystal structure of dehydrosqualene synthase (Crtm) from S. aureus complexed with diphosphate and quinuclidine BPH-651

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Sequence of
1    ​M​​T​​M​​M​​D​​M​​N​​F​​K​​Y​11   ​C​​H​​K​​I​​M​​K​​K​​H​​S​​K​21   ​S​​F​​S​​Y​​A​​F​​D​​L​​L​​P​31   ​E​​D​​Q​​R​​K​​A​​V​​W​​A​​I​41   ​Y​​A​​V​​C​​R​​K​​I​​D​​D​​S​51   ​I​​D​​V​​Y​​G​​D​​I​​Q​​F​​L​61   ​N​​Q​​I​​K​​E​​D​​I​​Q​​S​​I​71   ​E​​K​​Y​​P​​Y​​E​​Y​​H​​H​​F​81   ​Q​​S​​D​​R​​R​​I​​M​​M​​A​​L​91   ​Q​​H​​V​​A​​Q​​H​​K​​N​​I​​A​101  ​F​​Q​​S​​F​​Y​​N​​L​​I​​D​​T​111  ​V​​Y​​K​​D​​Q​​H​​F​​T​​M​​F​121  ​E​​T​​D​​A​​E​​L​​F​​G​​Y​​C​131  ​Y​​G​​V​​A​​G​​T​​V​​G​​E​​V​141  ​L​​T​​P​​I​​L​​S​​D​​H​​E​​T​151  ​H​​Q​​T​​Y​​D​​V​​A​​R​​R​​L​161  ​G​​E​​S​​L​​Q​​L​​I​​N​​I​​L​171  ​R​​D​​V​​G​​E​​D​​F​​E​​N​​E​181  ​R​​I​​Y​​F​​S​​K​​Q​​R​​L​​K​191  ​Q​​Y​​E​​V​​D​​I​​A​​E​​V​​Y​201  ​Q​​N​​G​​V​​N​​N​​H​​Y​​I​​D​211  ​L​​W​​E​​Y​​Y​​A​​A​​I​​A​​E​221  ​K​​D​​F​​R​​D​​V​​M​​D​​Q​​I​231  ​K​​V​​F​​S​​I​​E​​A​​Q​​P​​I​241  ​I​​E​​L​​A​​A​​R​​I​​Y​​I​​E​251  ​I​​L​​D​​E​​V​​R​​Q​​A​​N​​Y​261  ​T​​L​​H​​E​​R​​V​​F​​V​​E​​K​271  ​R​​K​​K​​A​​K​​L​​F​​H​​E​​I​281  ​N​​S​​K​​Y​​H​​R​​I​

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